Bioluminescence imaging

Imaging of engineered E. coli Nissle 1917 in the mouse gut

Bioluminescence imaging (BLI) is a technology developed over the past decades (1990's and onward).[1][2][3][when?] that allows for the noninvasive study of ongoing biological processes[4][1][5][6][7] Recently, bioluminescence tomography (BLT) has become possible and several systems have become commercially available. In 2011, PerkinElmer acquired one of the most popular lines of optical imaging systems with bioluminescence from Caliper Life Sciences.[8]

  1. ^ a b Zambito G, Chawda C, Mezzanotte L (August 2021). "Emerging tools for bioluminescence imaging". Current Opinion in Chemical Biology. Chemical Genetics and Epigenetics * Molecular Imaging. 63: 86–94. doi:10.1016/j.cbpa.2021.02.005. PMID 33770744. S2CID 232377256.
  2. ^ Contag CH, Bachmann MH (2002-08-01). "Advances in in vivo bioluminescence imaging of gene expression". Annual Review of Biomedical Engineering. 4 (1): 235–260. doi:10.1146/annurev.bioeng.4.111901.093336. PMID 12117758.
  3. ^ Mezzanotte L, van 't Root M, Karatas H, Goun EA, Löwik CW (July 2017). "In Vivo Molecular Bioluminescence Imaging: New Tools and Applications". Trends in Biotechnology. 35 (7): 640–652. doi:10.1016/j.tibtech.2017.03.012. PMID 28501458.
  4. ^ Brennan CK, Ornelas MY, Yao ZW, Prescher JA (August 2021). "Multicomponent Bioluminescence Imaging with Naphthylamino Luciferins". ChemBioChem. 22 (16): 2650–2654. doi:10.1002/cbic.202100202. PMC 8496354. PMID 34139065.
  5. ^ Syed AJ, Anderson JC (May 2021). "Applications of bioluminescence in biotechnology and beyond". Chemical Society Reviews. 50 (9): 5668–5705. doi:10.1039/D0CS01492C. PMID 33735357. S2CID 232304401.
  6. ^ Thorne N, Inglese J, Auld DS (June 2010). "Illuminating insights into firefly luciferase and other bioluminescent reporters used in chemical biology". Chemistry & Biology. 17 (6): 646–657. doi:10.1016/j.chembiol.2010.05.012. PMC 2925662. PMID 20609414.
  7. ^ Yeh HW, Ai HW (June 2019). "Development and Applications of Bioluminescent and Chemiluminescent Reporters and Biosensors". Annual Review of Analytical Chemistry. 12 (1): 129–150. Bibcode:2019ARAC...12..129Y. doi:10.1146/annurev-anchem-061318-115027. PMC 6565457. PMID 30786216.
  8. ^ "PerkinElmer to Acquire Caliper Life Sciences for $600M in Cash". Genetic Engineering & Biotechnology News (GEN). Mary Ann Liebert, Inc. 8 September 2011. Retrieved 2016-06-10.