Bombesin-like receptor 3

BRS3
Identifiers
Aliases	BRS3, BB3, bombesin like receptor 3, BB3R, bombesin receptor subtype 3, BBR3
External IDs	OMIM: 300107; MGI: 1100501; HomoloGene: 1307; GeneCards: BRS3; OMA:BRS3 - orthologs
Gene location (Human)
Chr.	X chromosome (human)
End	136,493,780 bp
Gene location (Mouse)
Chr.	X chromosome (mouse)
End	56,094,118 bp
RNA expression pattern
	Top expressed in
	buccal mucosa cell; ; corpus epididymis; ; testicle; ; caput epididymis; ; pancreatic ductal cell; ; islet of Langerhans; ; tail of epididymis; ; tibialis anterior muscle; ; right ovary; ; left uterine tube;
	Top expressed in
	gastrula; ; embryo; ; tibiofemoral joint; ; lumbar spinal ganglion; ; carotid body; ; nucleus of stria terminalis; ; central gray substance of midbrain; ; hypothalamus; ; neck; ; sternocleidomastoid muscle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	bombesin receptor activity; G protein-coupled peptide receptor activity; G protein-coupled receptor activity; signal transducer activity;
Cellular component	integral component of membrane; neuron projection; soma; plasma membrane; membrane; integral component of plasma membrane;
Biological process	regulation of blood pressure; G protein-coupled receptor signaling pathway; bombesin receptor signaling pathway; adult feeding behavior; signal transduction; glucose metabolic process;
	Sources:Amigo / QuickGO
Orthologs
	680
	12209
	ENSG00000102239
	ENSMUSG00000031130
	P32247
	O54798
	NM_001727
	NM_009766
	NP_001718
	NP_033896
	Wikidata
View/Edit Human	View/Edit Mouse

The bombesin receptor subtype 3 also known as BRS-3 or BB₃^[5] is a protein which in humans is encoded by the BRS3 gene.^[6]^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000102239 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000031130 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Bombesin Receptors: BB₃". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. Archived from the original on 2016-03-03. Retrieved 2007-10-25.
^ Fathi Z, Corjay MH, Shapira H, Wada E, Benya R, Jensen R, Viallet J, Sausville EA, Battey JF (March 1993). "BRS-3: a novel bombesin receptor subtype selectively expressed in testis and lung carcinoma cells". J. Biol. Chem. 268 (8): 5979–84. doi:10.1016/S0021-9258(18)53415-3. PMID 8383682.
^ Ohki-Hamazaki H, Wada E, Matsui K, Wada K (July 1997). "Cloning and expression of the neuromedin B receptor and the third subtype of bombesin receptor genes in the mouse". Brain Res. 762 (1–2): 165–72. doi:10.1016/S0006-8993(97)00380-6. PMID 9262170. S2CID 1012779.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000102239 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000031130 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[IUPHAR-DB-5] "Bombesin Receptors: BB₃". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. Archived from the original on 2016-03-03. Retrieved 2007-10-25.

[pmid8383682-6] Fathi Z, Corjay MH, Shapira H, Wada E, Benya R, Jensen R, Viallet J, Sausville EA, Battey JF (March 1993). "BRS-3: a novel bombesin receptor subtype selectively expressed in testis and lung carcinoma cells". J. Biol. Chem. 268 (8): 5979–84. doi:10.1016/S0021-9258(18)53415-3. PMID 8383682.

[pmid9262170-7] Ohki-Hamazaki H, Wada E, Matsui K, Wada K (July 1997). "Cloning and expression of the neuromedin B receptor and the third subtype of bombesin receptor genes in the mouse". Brain Res. 762 (1–2): 165–72. doi:10.1016/S0006-8993(97)00380-6. PMID 9262170. S2CID 1012779.

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