Brachial amyotrophic diplegia

Brachial amyotrophic diplegia, also called Vulpian-Bernhardt Syndrome (VBS), flail arm syndrome, or man-in-barrel syndrome, is a rare motor neuron disease, often considered to be a phenotype or regional variant of amyotrophic lateral sclerosis.[1] In the first twelve to eighteen months, only a progressive weakness of one or both arms is observed.[2] Within the spectrum of ALS, this subtype has a relatively longer survival time. Because of its distinct symptoms, it was suggested that VBS is a separate entity, different from ALS.

  1. ^ Jawdat, Omar; Statland, Jeffrey M.; Barohn, Richard J.; Katz, Jonathan; Dimachkie, Mazen M. (November 2015). "ALS Regional Variants (Brachial Amyotrophic Diplpegia, Leg Amyotrophic Diplegia, and Isolated Bulbar ALS)". Neurologic Clinics. 33 (4): 775–785. doi:10.1016/j.ncl.2015.07.003. ISSN 0733-8619. PMC 4629514. PMID 26515621.
  2. ^ Masrori, P.; Van Damme, P. (October 2010). "Amyotrophic lateral sclerosis: a clinical review". European Journal of Neurology. 27 (10): 1918–1929. doi:10.1111/ene.14393. ISSN 1351-5101. PMC 7540334. PMID 32526057.