Brain-specific angiogenesis inhibitor 1

ADGRB1
Identifiers
Aliases	ADGRB1, BAI1, GDAIF, adhesion G protein-coupled receptor B1
External IDs	OMIM: 602682; MGI: 1933736; HomoloGene: 1287; GeneCards: ADGRB1; OMA:ADGRB1 - orthologs
Gene location (Human)
Chr.	Chromosome 8 (human)
End	142,545,009 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	74,461,314 bp
RNA expression pattern
	Top expressed in
	right frontal lobe; ; nucleus accumbens; ; cingulate gyrus; ; anterior cingulate cortex; ; amygdala; ; Brodmann area 9; ; caudate nucleus; ; putamen; ; prefrontal cortex; ; right hemisphere of cerebellum;
	Top expressed in
	superior frontal gyrus; ; primary visual cortex; ; dentate gyrus of hippocampal formation granule cell; ; entorhinal cortex; ; perirhinal cortex; ; ventricular zone; ; neural layer of retina; ; CA3 field; ; cerebellar cortex; ; nucleus of stria terminalis;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	G protein-coupled receptor activity; signal transducer activity; transmembrane signaling receptor activity; lipopolysaccharide binding; phosphatidylserine binding; PDZ domain binding; protein binding;
Cellular component	integral component of membrane; integral component of plasma membrane; cell-cell junction; membrane; phagocytic cup; extracellular space; plasma membrane; focal adhesion; postsynaptic density; dendrite; perinuclear region of cytoplasm; extracellular region; cell junction; cell projection; dendritic spine; synapse; postsynaptic membrane;
Biological process	G protein-coupled receptor signaling pathway; cell surface receptor signaling pathway; peripheral nervous system development; axonogenesis; signal transduction; negative regulation of cell population proliferation; positive regulation of synapse assembly; phagocytosis, recognition; phagocytosis, engulfment; negative regulation of endothelial cell migration; negative regulation of angiogenesis; negative regulation of protein ubiquitination; negative regulation of protein catabolic process; apoptotic cell clearance; engulfment of apoptotic cell; regulation of synaptic plasticity; defense response to Gram-negative bacterium; positive regulation of myoblast fusion; positive regulation of reactive oxygen species biosynthetic process; immune system process; phagocytosis; cell adhesion; nervous system development; muscle organ development; innate immune response; adenylate cyclase-activating G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	575
	107831
	ENSG00000181790
	ENSMUSG00000034730
	O14514
	Q3UHD1
	NM_001702; NM_001391985; NM_001391986; NM_001391987; NM_001391988
	NM_174991; NM_001359759
	NP_001693
	NP_778156; NP_001346688
	Wikidata
View/Edit Human	View/Edit Mouse

Brain-specific angiogenesis inhibitor 1 is a protein that in humans is encoded by the BAI1 gene.^[5]^[6] It is a member of the adhesion-GPCR family of receptors.^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000181790 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000034730 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Shiratsuchi T, Nishimori H, Ichise H, Nakamura Y, Tokino T (Apr 1998). "Cloning and characterization of BAI2 and BAI3, novel genes homologous to brain-specific angiogenesis inhibitor 1 (BAI1)". Cytogenetics and Cell Genetics. 79 (1–2): 103–8. doi:10.1159/000134693. PMID 9533023.
^ Cite error: The named reference entrez was invoked but never defined (see the help page).
^ Stacey M, Yona S (2011). AdhesionGPCRs: Structure to Function (Advances in Experimental Medicine and Biology). Berlin: Springer. ISBN 978-1-4419-7912-4.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000181790 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000034730 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9533023-5] Shiratsuchi T, Nishimori H, Ichise H, Nakamura Y, Tokino T (Apr 1998). "Cloning and characterization of BAI2 and BAI3, novel genes homologous to brain-specific angiogenesis inhibitor 1 (BAI1)". Cytogenetics and Cell Genetics. 79 (1–2): 103–8. doi:10.1159/000134693. PMID 9533023.

[entrez-6] Cite error: The named reference entrez was invoked but never defined (see the help page).

[isbn1-4419-7912-3-7] Stacey M, Yona S (2011). AdhesionGPCRs: Structure to Function (Advances in Experimental Medicine and Biology). Berlin: Springer. ISBN 978-1-4419-7912-4.

[1]

[2]

[3]

[4]

[5]

[6]

[7]