Brant is a surname. Notable people with the surname include:
- Aaron Brant (b. 1984), American football player
- Alice Dayrell Caldeira Brant (1880–1970), Brazilian writer
- Antony Thomas Brant (b. 1983), English pop singer
- Berle Brant (b. 1989), Estonian footballer
- Beth Brant, Native Canadian Mohawk writer
- David Brant, NCIS investigator
- Everett H. Brant (1885–1954), American politician
- Henry Brant (1913–2008), Canadian-born composer, long-resident in the US
- Isabella Brant (1591–1626), first wife of Peter Paul Rubens
- John Brant (Mohawk chief) (1794–1832), Mohawk chief, son of Joseph
- Jon Brant (b. 1955), American bass player
- Joseph Brant (c. 1743–1807), Mohawk leader
- Lauren Brant (b. 1989), Australian TV personality, member of Hi-5
- Marshall Brant (b. 1955), American baseball player
- Molly Brant (c. 1736–1796), Mohawk leader
- Mike Brant (1947–1975), Israeli pop star
- Monica Brant (b. 1970), American bodybuilder
- Peter M. Brant (b. 1947), American art collector and film producer
- Scott Brant (cricketer) (b. 1983), Zimbabwean cricketer
- Scott Brant (speedway rider) (b. 1969), American speedway racer
- Sebastian Brant (1457–1521), German humanist and satirist
- Shawn Brant, Native Canadian Mohawk activist
- Tim Brant (b. 1949), American sportscaster