Braun's lipoprotein

Lipoprotein leucine-zipper
Identifiers
SymbolLPP
PfamPF04728
InterProIPR006817
CATH1jccA00
SCOP2d1jcca_ / SCOPe / SUPFAM
Available protein structures:
Pfam  structures / ECOD  
PDBRCSB PDB; PDBe; PDBj
PDBsumstructure summary
Use IPR016367 for full protein. E. coli protein is P69776.

Braun's lipoprotein (BLP, Lpp, murein lipoprotein, or major outer membrane lipoprotein), found in some gram-negative cell walls, is one of the most abundant membrane proteins; its molecular weight is about 7.2 kDa. It is bound at its C-terminal end (a lysine) by a covalent bond to the peptidoglycan layer (specifically to diaminopimelic acid molecules[1]) and is embedded in the outer membrane by its hydrophobic head (a cysteine with lipids attached). BLP tightly links the two layers and provides structural integrity to the outer membrane.

  1. ^ Seltmann, Guntram; Holst, Otto (2002). The Bacterial Cell Wall. Berlin: Springer. pp. 81–82. ISBN 3-540-42608-6.