Building block (chemistry)

Construction of complex molecular architectures is easily possible using simple building blocks

Building block is a term in chemistry which is used to describe a virtual molecular fragment or a real chemical compound the molecules of which possess reactive functional groups.[1] Building blocks are used for bottom-up modular assembly of molecular architectures: nano-particles,[2][3] metal-organic frameworks,[4] organic molecular constructs, supra-molecular complexes.[5] Using building blocks ensures strict control of what a final compound or a (supra)molecular construct will be.[6]

  1. ^ H.H. Szmant (1989). Organic Building Blocks of the Chemical Industry. New York: John Wiley & Sons.
  2. ^ L. Zang; Y. Che; J.S. Moore (2008). "One-Dimensional Self-Assembly of Planar π-Conjugated Molecules: Adaptable Building Blocks for Organic Nanodevices". Acc. Chem. Res. 41 (12): 1596–1608. doi:10.1021/ar800030w. PMID 18616298.
  3. ^ J.M.J. Fréchet (2003). "Dendrimers and other dendritic macromolecules: From building blocks to functional assemblies in nanoscience and nanotechnology". J. Polym. Sci. A Polym. Chem. 41 (23): 3713–3725. Bibcode:2003JPoSA..41.3713F. doi:10.1002/pola.10952.
  4. ^ O. K. Farha; C. D. Malliakas; M.G. Kanatzidis; J.T. Hupp (2010). "Control over Catenation in Metal−Organic Frameworks via Rational Design of the Organic Building Block". J. Am. Chem. Soc. 132 (3): 950–952. doi:10.1021/ja909519e. PMID 20039671.
  5. ^ A.J. Cairns; J.A. Perman; L. Wojtas; V.Ch. Kravtsov; M.H. Alkordi; M.Eddaoudi; M.J. Zaworotko (2008). "Supermolecular Building Blocks (SBBs) and Crystal Design: 12-Connected Open Frameworks Based on a Molecular Cubohemioctahedron". J. Am. Chem. Soc. 130 (5): 1560–1561. doi:10.1021/ja078060t. PMID 18186639.
  6. ^ R.S. Tu; M. Tirrell (2004). "Bottom-up design of biomimetic assemblies". Adv. Drug Deliv. Rev. 56 (11): 1537–1563. doi:10.1016/j.addr.2003.10.047. PMID 15350288.