CBARA1

MICU1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4NSC, 4NSD
Identifiers
Aliases	MICU1, CALC, CBARA1, EFHA3, MPXPS, mitochondrial calcium uptake 1, ara CALC
External IDs	OMIM: 605084; MGI: 2384909; HomoloGene: 4431; GeneCards: MICU1; OMA:MICU1 - orthologs
Gene location (Human)
Chr.	Chromosome 10 (human)
End	72,626,131 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	59,699,954 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; cerebellar hemisphere; ; right hemisphere of cerebellum; ; right adrenal cortex; ; monocyte; ; left adrenal gland; ; right frontal lobe; ; gastrocnemius muscle; ; left adrenal cortex; ; prefrontal cortex;
	Top expressed in
	intestinal villus; ; neural layer of retina; ; dentate gyrus of hippocampal formation granule cell; ; granulocyte; ; pyloric antrum; ; lens; ; mucous cell of stomach; ; zygote; ; duodenum; ; muscle of thigh;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	calcium ion binding; metal ion binding; protein binding; identical protein binding; protein heterodimerization activity;
Cellular component	calcium channel complex; membrane; mitochondrial intermembrane space; intracellular anatomical structure; mitochondrion; uniplex complex; integral component of mitochondrial membrane; integral component of membrane; mitochondrial inner membrane;
Biological process	defense response; calcium ion import; mitochondrial calcium ion homeostasis; ion transport; calcium import into the mitochondrion; positive regulation of mitochondrial calcium ion concentration; protein homooligomerization; calcium ion transport; mitochondrial calcium ion transmembrane transport; regulation of cellular hyperosmotic salinity response;
	Sources:Amigo / QuickGO
Orthologs
	10367
	216001
	ENSG00000107745
	ENSMUSG00000020111
	Q9BPX6
	Q8VCX5
	NM_001195518; NM_001195519; NM_006077; NM_001363513
	NM_001291442; NM_001291443; NM_144822; NM_001359267
	NP_001182447; NP_001182448; NP_006068; NP_001350442
	NP_001278371; NP_001278372; NP_659071; NP_001346196
	Wikidata
View/Edit Human	View/Edit Mouse

Calcium-binding atopy-related autoantigen 1 is a protein that in humans is encoded by the CBARA1 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000107745 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000020111 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Natter S, Seiberler S, Hufnagl P, Binder BR, Hirschl AM, Ring J, Abeck D, Schmidt T, Valent P, Valenta R (Nov 1998). "Isolation of cDNA clones coding for IgE autoantigens with serum IgE from atopic dermatitis patients". FASEB J. 12 (14): 1559–69. doi:10.1096/fasebj.12.14.1559. PMID 9806765. S2CID 18002244.
^ "Entrez Gene: CBARA1 calcium binding atopy-related autoantigen 1".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000107745 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000020111 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9806765-5] Natter S, Seiberler S, Hufnagl P, Binder BR, Hirschl AM, Ring J, Abeck D, Schmidt T, Valent P, Valenta R (Nov 1998). "Isolation of cDNA clones coding for IgE autoantigens with serum IgE from atopic dermatitis patients". FASEB J. 12 (14): 1559–69. doi:10.1096/fasebj.12.14.1559. PMID 9806765. S2CID 18002244.

[entrez-6] "Entrez Gene: CBARA1 calcium binding atopy-related autoantigen 1".

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