CBFA2T2

CBFA2T2
Identifiers
Aliases	CBFA2T2, EHT, MTGR1, ZMYND3, p85, CBFA2/RUNX1 translocation partner 2, CBFA2/RUNX1 partner transcriptional co-repressor 2
External IDs	OMIM: 603672; MGI: 1333833; HomoloGene: 3733; GeneCards: CBFA2T2; OMA:CBFA2T2 - orthologs
Gene location (Human)
Chr.	Chromosome 20 (human)
End	33,650,036 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	154,381,276 bp
RNA expression pattern
	Top expressed in
	buccal mucosa cell; ; ganglionic eminence; ; middle temporal gyrus; ; sural nerve; ; lateral nuclear group of thalamus; ; pars reticulata; ; external globus pallidus; ; tendon of biceps brachii; ; prostate; ; subthalamic nucleus;
	Top expressed in
	substantia nigra; ; Paneth cell; ; ventricular zone; ; fossa; ; barrel cortex; ; ganglionic eminence; ; cingulate gyrus; ; condyle; ; epithelium of lens; ; tail of embryo;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	DNA-binding transcription factor activity; protein binding; transcription corepressor activity; metal ion binding;
Cellular component	nucleus;
Biological process	negative regulation of neuron projection development; negative regulation of transcription, DNA-templated; regulation of transcription, DNA-templated; epithelial cell differentiation; transcription, DNA-templated; positive regulation of neuron projection development; negative regulation of transcription by RNA polymerase II; negative regulation of Notch signaling pathway; intestinal epithelial cell differentiation;
	Sources:Amigo / QuickGO
Orthologs
	9139
	12396
	ENSG00000078699
	ENSMUSG00000038533
	O43439
	O70374
	NM_001032999; NM_001039709; NM_005093; NM_175864
	NM_001285446; NM_009823; NM_172860
	NP_001028171; NP_001034798; NP_005084
	NP_001272375; NP_033953; NP_766448
	Wikidata
View/Edit Human	View/Edit Mouse

Protein CBFA2T2 is a protein that in humans is encoded by the CBFA2T2 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000078699 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000038533 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Calabi F, Cilli V (December 1998). "CBFA2T1, a gene rearranged in human leukemia, is a member of a multigene family". Genomics. 52 (3): 332–41. doi:10.1006/geno.1998.5429. PMID 9790752.
^ "Entrez Gene: CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000078699 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000038533 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9790752-5] Calabi F, Cilli V (December 1998). "CBFA2T1, a gene rearranged in human leukemia, is a member of a multigene family". Genomics. 52 (3): 332–41. doi:10.1006/geno.1998.5429. PMID 9790752.

[entrez-6] "Entrez Gene: CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2".

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