CBFA2T3

CBFA2T3
Identifiers
Aliases	CBFA2T3, ETO2, MTG16, MTGR2, ZMYND4, RUNX1T3, CBFA2/RUNX1 translocation partner 3, CBFA2/RUNX1 partner transcriptional co-repressor 3
External IDs	OMIM: 603870; MGI: 1338013; HomoloGene: 74543; GeneCards: CBFA2T3; OMA:CBFA2T3 - orthologs
Gene location (Human)
Chr.	Chromosome 16 (human)
End	88,977,207 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	123,425,848 bp
RNA expression pattern
	Top expressed in
	right hemisphere of cerebellum; ; thymus; ; apex of heart; ; monocyte; ; granulocyte; ; body of pancreas; ; spleen; ; right lung; ; paraflocculus of cerebellum; ; bone marrow cells;
	Top expressed in
	internal carotid artery; ; external carotid artery; ; cumulus cell; ; tibiofemoral joint; ; aortic valve; ; muscle of thigh; ; lumbar subsegment of spinal cord; ; ascending aorta; ; thymus; ; blood;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA-binding transcription factor activity; protein binding; metal ion binding; transcription corepressor activity;
Cellular component	Golgi membrane; Golgi apparatus; nucleolus; membrane; nucleus; nucleoplasm;
Biological process	regulation of aerobic respiration; cell differentiation; cell population proliferation; negative regulation of glycolytic process; response to hypoxia; granulocyte differentiation; regulation of transcription, DNA-templated; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; transcription, DNA-templated; negative regulation of cell population proliferation; negative regulation of transcription, DNA-templated;
	Sources:Amigo / QuickGO
Orthologs
	863
	12398
	ENSG00000129993
	ENSMUSG00000006362
	O75081
	O54972
	NM_005187; NM_175931
	NM_001109873; NM_009824; NM_177289
	NP_005178; NP_787127
	NP_001103343; NP_033954; NP_796263
	Wikidata
View/Edit Human	View/Edit Mouse

Protein CBFA2T3 (core-binding factor, runt domain, alpha subunit 2; translocated to, 3) is a protein that in humans is encoded by the CBFA2T3 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000129993 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000006362 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Calabi F, Cilli V (Dec 1998). "CBFA2T1 (core-binding factor, runt domain, alpha subunit 2; translocated to, 3), a gene rearranged in human leukemia, is a member of a multigene family". Genomics. 52 (3): 332–41. doi:10.1006/geno.1998.5429. PMID 9790752.
^ "Entrez Gene: CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000129993 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000006362 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9790752-5] Calabi F, Cilli V (Dec 1998). "CBFA2T1 (core-binding factor, runt domain, alpha subunit 2; translocated to, 3), a gene rearranged in human leukemia, is a member of a multigene family". Genomics. 52 (3): 332–41. doi:10.1006/geno.1998.5429. PMID 9790752.

[entrez-6] "Entrez Gene: CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3".

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