CCL7

CCL7
Available structures PDB Human UniProt search: PDBe RCSB List of PDB id codes 1BO0, 1NCV, 4ZKC
Identifiers
Aliases	CCL7, FIC, MARC, MCP-3, MCP3, NC28, SCYA6, SCYA7, C-C motif chemokine ligand 7
External IDs	OMIM: 158106; HomoloGene: 4568; GeneCards: CCL7; OMA:CCL7 - orthologs
Gene location (Human) Chr. Chromosome 17 (human)[1] Band 17q12 Start 34,270,221 bp[1] End 34,272,242 bp[1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in islet of Langerhans mucosa of urinary bladder stromal cell of endometrium amniotic fluid cartilage tissue appendix rectum smooth muscle tissue lower lobe of lung parietal pleura n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function cytokine activity heparin binding chemokine activity CCR1 chemokine receptor binding protein binding CCR2 chemokine receptor binding CCR chemokine receptor binding Cellular component extracellular region extracellular space Biological process G protein-coupled receptor signaling pathway monocyte chemotaxis positive regulation of cell migration positive regulation of natural killer cell chemotaxis chemokine-mediated signaling pathway cellular response to tumor necrosis factor cell-cell signaling eosinophil chemotaxis cellular calcium ion homeostasis neutrophil chemotaxis chemotaxis positive regulation of GTPase activity cytoskeleton organization cellular response to interleukin-1 immune response positive regulation of ERK1 and ERK2 cascade regulation of cell shape cellular response to interferon-gamma inflammatory response signal transduction response to gamma radiation cellular response to ethanol regulation of signaling receptor activity lymphocyte chemotaxis Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 6354 n/a Ensembl ENSG00000108688 n/a UniProt P80098 n/a RefSeq (mRNA) NM_006273 n/a RefSeq (protein) NP_006264 n/a Location (UCSC) Chr 17: 34.27 – 34.27 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human

Chemokine (C-C motif) ligand 7 (CCL7) is a small cytokine that was previously called monocyte-chemotactic protein 3 (MCP3). CCL7 is a small protein that belongs to the CC chemokine family and is most closely related to CCL2 (previously called MCP1).^[3]