C-C chemokine receptor type 9 is a protein that in humans is encoded by the CCR9 gene.[5][6] This gene is mapped to the chemokine receptor gene cluster region. Two alternatively spliced transcript variants have been described.[6]
CCR9 has also recently been designated CDw199 (cluster of differentiation w199).
The protein encoded by this gene is a member of the beta chemokine receptor family. CCR9 is a seven transmembrane protein similar to G protein-coupled receptors.[7][8][9]
- ^ a b c GRCh38: Ensembl release 89: ENSG00000173585 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000029530 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Zaballos A, Gutiérrez J, Varona R, Ardavín C, Márquez G (May 1999). "Cutting edge: identification of the orphan chemokine receptor GPR-9-6 as CCR9, the receptor for the chemokine TECK". Journal of Immunology. 162 (10): 5671–5675. doi:10.4049/jimmunol.162.10.5671. PMID 10229797. S2CID 21522407.
- ^ a b "Entrez Gene: CCR9 chemokine (C-C motif) receptor 9".
- ^ Schulz O, Hammerschmidt SI, Moschovakis GL, Förster R (May 2016). "Chemokines and Chemokine Receptors in Lymphoid Tissue Dynamics". Annual Review of Immunology. 34 (1): 203–242. doi:10.1146/annurev-immunol-041015-055649. PMID 26907216.
- ^ Griffith JW, Sokol CL, Luster AD (2014-03-21). "Chemokines and chemokine receptors: positioning cells for host defense and immunity". Annual Review of Immunology. 32 (1): 659–702. doi:10.1146/annurev-immunol-032713-120145. PMID 24655300. S2CID 10579265.
- ^ Tu Z, Xiao R, Xiong J, Tembo KM, Deng X, Xiong M, et al. (February 2016). "CCR9 in cancer: oncogenic role and therapeutic targeting". Journal of Hematology & Oncology. 9 (1): 10. doi:10.1186/s13045-016-0236-7. PMC 4754913. PMID 26879872.