CDH15

CDH15
Identifiers
Aliases	CDH15, CDH14, CDH3, CDHM, MCAD, MRD3, cadherin 15
External IDs	OMIM: 114019; MGI: 106672; HomoloGene: 3622; GeneCards: CDH15; OMA:CDH15 - orthologs
Gene location (Human)
Chr.	Chromosome 16 (human)
End	89,195,492 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	123,594,136 bp
RNA expression pattern
	Top expressed in
	cerebellar hemisphere; ; right hemisphere of cerebellum; ; gastrocnemius muscle; ; muscle of thigh; ; Skeletal muscle tissue of rectus abdominis; ; glutes; ; tibialis anterior muscle; ; deltoid muscle; ; paraflocculus of cerebellum; ; tibia;
	Top expressed in
	myotome; ; muscle of thigh; ; lumbar spinal ganglion; ; temporal muscle; ; triceps brachii muscle; ; vastus lateralis muscle; ; body of femur; ; ankle; ; internal carotid artery; ; sternocleidomastoid muscle;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	calcium ion binding; protein binding; metal ion binding; cytoskeletal protein binding; protein homodimerization activity; cadherin binding;
Cellular component	caveola; integral component of membrane; neuromuscular junction; plasma membrane; extracellular exosome; membrane; Golgi apparatus; cytosol; cell surface; catenin complex;
Biological process	cell adhesion; adherens junction organization; positive regulation of muscle cell differentiation; homophilic cell adhesion via plasma membrane adhesion molecules; cell morphogenesis; cell-cell junction assembly; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules; cell-cell adhesion mediated by cadherin; cell-cell adhesion;
	Sources:Amigo / QuickGO
Orthologs
	1013
	12555
	ENSG00000129910
	ENSMUSG00000031962
	P55291
	P33146
	NM_004933
	NM_007662
	NP_004924
	NP_031688
	Wikidata
View/Edit Human	View/Edit Mouse

Cadherin-15 is a protein that in humans is encoded by the CDH15 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000129910 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000031962 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Kaupmann K, Becker-Follmann J, Scherer G, Jockusch H, Starzinski-Powitz A (December 1992). "The gene for the cell adhesion molecule M-cadherin maps to mouse chromosome 8 and human chromosome 16q24.1-qter and is near the E-cadherin (uvomorulin) locus in both species". Genomics. 14 (2): 488–90. doi:10.1016/S0888-7543(05)80247-2. PMID 1427864.
^ "Entrez Gene: CDH15 cadherin 15, M-cadherin (myotubule)".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000129910 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000031962 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid1427864-5] Kaupmann K, Becker-Follmann J, Scherer G, Jockusch H, Starzinski-Powitz A (December 1992). "The gene for the cell adhesion molecule M-cadherin maps to mouse chromosome 8 and human chromosome 16q24.1-qter and is near the E-cadherin (uvomorulin) locus in both species". Genomics. 14 (2): 488–90. doi:10.1016/S0888-7543(05)80247-2. PMID 1427864.

[entrez-6] "Entrez Gene: CDH15 cadherin 15, M-cadherin (myotubule)".

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