CDH8

CDH8
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1ZXK, 2A62
Identifiers
Aliases	CDH8, Nbla04261, cadherin 8
External IDs	OMIM: 603008; MGI: 107434; HomoloGene: 55604; GeneCards: CDH8; OMA:CDH8 - orthologs
Gene location (Human)
Chr.	Chromosome 16 (human)
End	62,037,035 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	100,143,103 bp
RNA expression pattern
	Top expressed in
	endothelial cell; ; Brodmann area 23; ; prefrontal cortex; ; lateral nuclear group of thalamus; ; entorhinal cortex; ; gonad; ; middle temporal gyrus; ; testicle; ; dorsolateral prefrontal cortex; ; Brodmann area 9;
	Top expressed in
	habenula; ; lateral septal nucleus; ; globus pallidus; ; dorsal tegmental nucleus; ; ventral tegmental area; ; medial dorsal nucleus; ; lateral hypothalamus; ; dentate gyrus of hippocampal formation granule cell; ; medial vestibular nucleus; ; lateral geniculate nucleus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	calcium ion binding; metal ion binding; identical protein binding; cytoskeletal protein binding; protein homodimerization activity; cadherin binding;
Cellular component	axon terminus; integral component of membrane; synaptic cleft; membrane; plasma membrane; synaptic membrane; glutamatergic synapse; cell surface; catenin complex;
Biological process	response to cold; cell adhesion; adherens junction organization; synaptic transmission, glutamatergic; homophilic cell adhesion via plasma membrane adhesion molecules; chemical synaptic transmission; regulation of synapse organization; cell-cell junction assembly; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules; cell-cell adhesion mediated by cadherin; cell-cell adhesion; cell morphogenesis;
	Sources:Amigo / QuickGO
Orthologs
	1006
	12564
	ENSG00000150394
	ENSMUSG00000036510
	P55286
	P97291
	NM_001796
	NM_001039154; NM_001285913; NM_001285914; NM_007667
	NP_001787
	NP_001034243; NP_001272842; NP_001272843; NP_031693
	Wikidata
View/Edit Human	View/Edit Mouse

Cadherin-8 is a protein that in humans is encoded by the CDH8 gene.^[5]^[6]^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000150394 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000036510 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Kremmidiotis G, Baker E, Crawford J, Eyre HJ, Nahmias J, Callen DF (May 1998). "Localization of human cadherin genes to chromosome regions exhibiting cancer-related loss of heterozygosity". Genomics. 49 (3): 467–471. doi:10.1006/geno.1998.5281. PMID 9615235.
^ Suzuki S, Sano K, Tanihara H (April 1991). "Diversity of the cadherin family: evidence for eight new cadherins in nervous tissue". Cell Regulation. 2 (4): 261–270. doi:10.1091/mbc.2.4.261. PMC 361775. PMID 2059658.
^ "Entrez Gene: CDH8 cadherin 8, type 2".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000150394 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000036510 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9615235-5] Kremmidiotis G, Baker E, Crawford J, Eyre HJ, Nahmias J, Callen DF (May 1998). "Localization of human cadherin genes to chromosome regions exhibiting cancer-related loss of heterozygosity". Genomics. 49 (3): 467–471. doi:10.1006/geno.1998.5281. PMID 9615235.

[pmid2059658-6] Suzuki S, Sano K, Tanihara H (April 1991). "Diversity of the cadherin family: evidence for eight new cadherins in nervous tissue". Cell Regulation. 2 (4): 261–270. doi:10.1091/mbc.2.4.261. PMC 361775. PMID 2059658.

[entrez-7] "Entrez Gene: CDH8 cadherin 8, type 2".

[1]

[2]

[3]

[4]

[5]

[6]

[7]