CLASP1

CLASP1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4K92
Identifiers
Aliases	CLASP1, MAST1, cytoplasmic linker associated protein 1
External IDs	OMIM: 605852; MGI: 1923957; HomoloGene: 41024; GeneCards: CLASP1; OMA:CLASP1 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	121,649,476 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	118,612,678 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; dorsal motor nucleus of vagus nerve; ; spinal ganglia; ; Region I of hippocampus proper; ; postcentral gyrus; ; cerebellar vermis; ; corpus callosum; ; inferior olivary nucleus; ; lateral nuclear group of thalamus; ; entorhinal cortex;
	Top expressed in
	myocardium of ventricle; ; right ventricle; ; cardiac muscles; ; atrium; ; atrioventricular valve; ; Rostral migratory stream; ; epithelium of lens; ; median eminence; ; pontine nuclei; ; superior cervical ganglion;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	kinetochore binding; dystroglycan binding; microtubule binding; microtubule plus-end binding; protein binding;
Cellular component	cytoplasm; cytosol; centrosome; Golgi apparatus; kinetochore microtubule; membrane; cortical microtubule cytoskeleton; focal adhesion; spindle; centrosomal corona; chromosome; microtubule plus-end; microtubule organizing center; cell cortex; spindle microtubule; cytoplasmic microtubule; basal cortex; extracellular exosome; chromosome, centromeric region; cytoskeleton; microtubule; kinetochore;
Biological process	establishment of epithelial cell polarity; vesicle targeting; Golgi organization; mitotic spindle organization; regulation of epithelial to mesenchymal transition; regulation of microtubule cytoskeleton organization; positive regulation of epithelial cell migration; exit from mitosis; cell division; establishment or maintenance of cell polarity; positive regulation of extracellular matrix disassembly; positive regulation of basement membrane assembly involved in embryonic body morphogenesis; negative regulation of microtubule depolymerization; mitotic spindle assembly; microtubule anchoring; G2/M transition of mitotic cell cycle; microtubule bundle formation; negative regulation of microtubule polymerization or depolymerization; positive regulation of microtubule polymerization; regulation of focal adhesion assembly; negative regulation of wound healing, spreading of epidermal cells; cell cycle; positive regulation of exocytosis; negative regulation of stress fiber assembly; establishment of spindle orientation; astral microtubule organization; microtubule organizing center organization; establishment of mitotic spindle localization; regulation of gastrulation; microtubule cytoskeleton organization; microtubule nucleation; sister chromatid cohesion; ciliary basal body-plasma membrane docking; regulation of G2/M transition of mitotic cell cycle;
	Sources:Amigo / QuickGO
Orthologs
	23332
	76707
	ENSG00000074054
	ENSMUSG00000064302
	Q7Z460
	Q80TV8
NM_001142273; NM_001142274; NM_001207051; NM_015282; NM_001378003;
	NM_001378004; NM_001378005; NM_001395891
NM_001081276; NM_001293300; NM_001293301; NM_029709; NM_177548;
	NM_001359328; NM_001359329; NM_001359330; NM_001359331; NM_001359334; NM_001359335; NM_001359336; NM_001359337; NM_001359338; NM_001359339; NM_001359340; NM_001359341; NM_001359342; NM_001359343; NM_001359345; NM_001359346; NM_001359347
NP_001135745; NP_001135746; NP_001193980; NP_056097; NP_001364932;
	NP_001364933; NP_001364934
NP_001280229; NP_001280230; NP_083985; NP_001346257; NP_001346258;
	NP_001346259; NP_001346260; NP_001346263; NP_001346264; NP_001346265; NP_001346266; NP_001346267; NP_001346268; NP_001346269; NP_001346270; NP_001346271; NP_001346272; NP_001346274; NP_001346275; NP_001346276
	Wikidata
View/Edit Human	View/Edit Mouse

Cytoplasmic linker associated protein 1, also known as CLASP1, is a protein which in humans is encoded by the CLASP1 gene.^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000074054 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000064302 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: CLASP1 cytoplasmic linker associated protein 1".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000074054 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000064302 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: CLASP1 cytoplasmic linker associated protein 1".

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