CLK1

CLK1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1Z57, 2VAG, 5J1V, 5J1W
Identifiers
Aliases	CLK1, CLK, CLK/STY, STY, CDC like kinase 1
External IDs	OMIM: 601951; MGI: 107403; HomoloGene: 101535; GeneCards: CLK1; OMA:CLK1 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	200,864,691 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	58,463,225 bp
RNA expression pattern
	Top expressed in
	granulocyte; ; right uterine tube; ; right ovary; ; left ovary; ; tibial nerve; ; anterior pituitary; ; C1 segment; ; left lobe of thyroid gland; ; canal of the cervix; ; gastric mucosa;
	Top expressed in
	granulocyte; ; neural layer of retina; ; pineal gland; ; spleen; ; lymph node; ; left lung lobe; ; superior cervical ganglion; ; blood; ; tunica media of zone of aorta; ; skin of external ear;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transferase activity; nucleotide binding; protein serine/threonine/tyrosine kinase activity; protein serine/threonine kinase activity; protein kinase activity; protein tyrosine kinase activity; non-membrane spanning protein tyrosine kinase activity; protein binding; ATP binding; kinase activity;
Cellular component	cytoplasm; nucleus;
Biological process	protein autophosphorylation; peptidyl-tyrosine phosphorylation; regulation of RNA splicing; protein phosphorylation; cell population proliferation; peptidyl-threonine phosphorylation; peptidyl-serine phosphorylation; phosphorylation;
	Sources:Amigo / QuickGO
Orthologs
	1195
	12747
	ENSG00000013441
	ENSMUSG00000026034
	P49759
	P22518
	NM_001024646; NM_001162407; NM_004071
	NM_001042634; NM_009905
	NP_001155879; NP_004062
	NP_001036099
	Wikidata
View/Edit Human	View/Edit Mouse

Dual specificity protein kinase CLK1 is an enzyme that in humans is encoded by the CLK1 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000013441 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000026034 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Talmadge CB, Finkernagel S, Sumegi J, Sciorra L, Rabinow L (Dec 1998). "Chromosomal mapping of three human LAMMER protein-kinase-encoding genes". Hum Genet. 103 (4): 523–4. doi:10.1007/s004390050861. PMID 9856501. S2CID 40593571.
^ Cite error: The named reference entrez was invoked but never defined (see the help page).

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000013441 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000026034 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9856501-5] Talmadge CB, Finkernagel S, Sumegi J, Sciorra L, Rabinow L (Dec 1998). "Chromosomal mapping of three human LAMMER protein-kinase-encoding genes". Hum Genet. 103 (4): 523–4. doi:10.1007/s004390050861. PMID 9856501. S2CID 40593571.

[entrez-6] Cite error: The named reference entrez was invoked but never defined (see the help page).

[1]

[2]

[3]

[4]

[5]

[6]