Chemokine like receptor 1 also known as ChemR23 (Chemerin Receptor 23) is a protein that in humans is encoded by the CMKLR1 gene.[5][6] Chemokine receptor-like 1 is a G protein-coupled receptor for the chemoattractant adipokine chemerin[7] and the omega-3 fatty acid eicosapentaenoic acid-derived specialized pro-resolving molecule, resolvin E1 (see Specialized proresolving mediators#EPA-derived resolvins (i.e. RvE)).[8] The murine receptor that shares almost 80% homology with the human receptor, is called Dez.[9]
- ^ a b c GRCh38: Ensembl release 89: ENSG00000174600 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000042190 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Entrez Gene: CMKLR1 chemokine-like receptor 1".
- ^ Gantz I, Konda Y, Yang YK, Miller DE, Dierick HA, Yamada T (1996). "Molecular cloning of a novel receptor (CMKLR1) with homology to the chemotactic factor receptors". Cytogenetics and Cell Genetics. 74 (4): 286–90. doi:10.1159/000134436. PMID 8976386.
- ^ Wittamer V, Franssen JD, Vulcano M, Mirjolet JF, Le Poul E, Migeotte I, Brézillon S, Tyldesley R, Blanpain C, Detheux M, Mantovani A, Sozzani S, Vassart G, Parmentier M, Communi D (October 2003). "Specific recruitment of antigen-presenting cells by chemerin, a novel processed ligand from human inflammatory fluids". The Journal of Experimental Medicine. 198 (7): 977–85. doi:10.1084/jem.20030382. PMC 2194212. PMID 14530373.
- ^ Arita M, Bianchini F, Aliberti J, Sher A, Chiang N, Hong S, Yang R, Petasis NA, Serhan CN (March 2005). "Stereochemical assignment, antiinflammatory properties, and receptor for the omega-3 lipid mediator resolvin E1". The Journal of Experimental Medicine. 201 (5): 713–22. doi:10.1084/jem.20042031. PMC 2212834. PMID 15753205.
- ^ Methner A, Hermey G, Schinke B, Hermans-Borgmeyer I (April 1997). "A novel G protein-coupled receptor with homology to neuropeptide and chemoattractant receptors expressed during bone development". Biochemical and Biophysical Research Communications. 233 (2): 336–42. doi:10.1006/bbrc.1997.6455. PMID 9144535.