CNBP

CNBP
Identifiers
Aliases	CNBP, CNBP1, DM2, PROMM, RNF163, ZCCHC22, ZNF9, CCHC-type zinc finger nucleic acid binding protein
External IDs	OMIM: 116955; MGI: 88431; HomoloGene: 2567; GeneCards: CNBP; OMA:CNBP - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	129,183,922 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	87,828,088 bp
RNA expression pattern
	Top expressed in
	Skeletal muscle tissue of rectus abdominis; ; thoracic diaphragm; ; biceps brachii; ; Skeletal muscle tissue of biceps brachii; ; oocyte; ; Achilles tendon; ; gastrocnemius muscle; ; seminal vesicula; ; parotid gland; ; tail of epididymis;
	Top expressed in
	otic placode; ; saccule; ; otic vesicle; ; primitive streak; ; endothelial cell of lymphatic vessel; ; abdominal wall; ; hair follicle; ; vestibular sensory epithelium; ; triceps brachii muscle; ; vastus lateralis muscle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; nucleic acid binding; zinc ion binding; DNA-binding transcription factor activity; metal ion binding; DNA binding; single-stranded DNA binding; single-stranded RNA binding; RNA binding; RNA polymerase II transcription regulatory region sequence-specific DNA binding; DNA-binding transcription repressor activity, RNA polymerase II-specific; mRNA binding; translation regulator activity;
Cellular component	nucleus; cytoplasm; endoplasmic reticulum; cytosol;
Biological process	regulation of transcription, DNA-templated; cholesterol biosynthetic process; transcription, DNA-templated; positive regulation of transcription by RNA polymerase II; positive regulation of transcription, DNA-templated; positive regulation of cell population proliferation; negative regulation of transcription by RNA polymerase II; positive regulation of cytoplasmic translation;
	Sources:Amigo / QuickGO
Orthologs
	7555
	12785
	ENSG00000169714
	ENSMUSG00000030057
	P62633
	P53996
NM_003418; NM_001127192; NM_001127193; NM_001127194; NM_001127195;
	NM_001127196
	NM_001109745; NM_001109746; NM_013493; NM_001347325; NM_001355195
NP_001120664; NP_001120665; NP_001120666; NP_001120667; NP_001120668;
	NP_003409
	NP_001103215; NP_001103216; NP_001334254; NP_038521; NP_001342124
	Wikidata
View/Edit Human	View/Edit Mouse

Cellular nucleic acid-binding protein is a protein that in humans is encoded by the CNBP gene.^[5]^[6]^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000169714 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000030057 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Lusis AJ, Rajavashisth TB, Klisak I, Heinzmann C, Mohandas T, Sparkes RS (Oct 1990). "Mapping of the gene for CNBP, a finger protein, to human chromosome 3q13.3-q24". Genomics. 8 (2): 411–4. doi:10.1016/0888-7543(90)90303-C. PMID 2249857.
^ Liquori CL, Ricker K, Moseley ML, Jacobsen JF, Kress W, Naylor SL, Day JW, Ranum LP (Aug 2001). "Myotonic dystrophy type 2 caused by a CCTG expansion in intron 1 of ZNF9". Science. 293 (5531): 864–7. doi:10.1126/science.1062125. PMID 11486088. S2CID 30903810.
^ "Entrez Gene: CNBP CCHC-type zinc finger, nucleic acid binding protein".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000169714 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000030057 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid2249857-5] Lusis AJ, Rajavashisth TB, Klisak I, Heinzmann C, Mohandas T, Sparkes RS (Oct 1990). "Mapping of the gene for CNBP, a finger protein, to human chromosome 3q13.3-q24". Genomics. 8 (2): 411–4. doi:10.1016/0888-7543(90)90303-C. PMID 2249857.

[pmid11486088-6] Liquori CL, Ricker K, Moseley ML, Jacobsen JF, Kress W, Naylor SL, Day JW, Ranum LP (Aug 2001). "Myotonic dystrophy type 2 caused by a CCTG expansion in intron 1 of ZNF9". Science. 293 (5531): 864–7. doi:10.1126/science.1062125. PMID 11486088. S2CID 30903810.

[entrez-7] "Entrez Gene: CNBP CCHC-type zinc finger, nucleic acid binding protein".

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