CURB-65

CURB-65
Symptom Points
Confusion 1
BUN>7 mmol/L (19 mg/dL) 1
Respiratory rate≥30 1
BP: S<90mmHg, D≤60mmHg 1
Age≥65 1

CURB-65, also known as the CURB criteria, is a clinical prediction rule that has been validated for predicting mortality in community-acquired pneumonia[1] and infection of any site.[2] The CURB-65 is based on the earlier CURB score[3] and is recommended by the British Thoracic Society for the assessment of severity of pneumonia.[4] It was developed in 2002 at the University of Nottingham by Dr. W.S. Lim et al.[1] In 2018 a new toolkit was presented on the basis of CURB-65.[5]

The score is an acronym for each of the risk factors measured. Each risk factor scores one point, for a maximum score of 5:

  • Confusion of new onset (defined as an AMTS of 8 or less)
  • Blood Urea nitrogen greater than 7 mmol/L (19 mg/dL)
  • Respiratory rate of 30 breaths per minute or greater
  • Blood pressure less than 90 mmHg systolic or diastolic blood pressure 60 mmHg or less
  • Age 65 or older
  1. ^ a b Lim WS, van der Eerden MM, Laing R, et al. (2003). "Defining community acquired pneumonia severity on presentation to hospital: an international derivation and validation study". Thorax. 58 (5): 377–82. doi:10.1136/thorax.58.5.377. PMC 1746657. PMID 12728155.
  2. ^ Howell MD, Donnino MW, Talmor D, Clardy P, Ngo L, Shapiro NI (2007). "Performance of severity of illness scoring systems in emergency department patients with infection". Academic Emergency Medicine. 14 (8): 709–14. doi:10.1197/j.aem.2007.02.036. PMID 17576773.
  3. ^ Lim WS, Macfarlane JT, Boswell TC, et al. (2001). "Study of community acquired pneumonia aetiology (SCAPA) in adults admitted to hospital: implications for management guidelines". Thorax. 56 (4): 296–301. doi:10.1136/thorax.56.4.296. PMC 1746017. PMID 11254821.
  4. ^ British Thoracic Society Standards of Care Committee (2001). "BTS Guidelines for the Management of Community Acquired Pneumonia in Adults". Thorax. 56. Suppl 4 (Suppl 4): IV1–64. doi:10.1136/thx.56.suppl_4.iv1. PMC 1765992. PMID 11713364.
  5. ^ Agency for Healthcare Research and Quality, Rockville, MD. (2018). "Community-Acquired Pneumonia Clinical Decision Support Implementation Toolkit. Content last reviewed January 2018".{{cite web}}: CS1 maint: multiple names: authors list (link)