CUTL1

CUX1
Identifiers
Aliases	CUX1, CASP, CDP, CDP/Cut, CDP1, COY1, CUTL1, CUX, Clox, Cux/CDP, GOLIM6, Nbla10317, p100, p110, p200, p75, cut like homeobox 1, GDDI
External IDs	OMIM: 116896; HomoloGene: 22551; GeneCards: CUX1; OMA:CUX1 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	102,283,958 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; buccal mucosa cell; ; stromal cell of endometrium; ; ganglionic eminence; ; right hemisphere of cerebellum; ; right coronary artery; ; sural nerve; ; myometrium; ; body of uterus; ; apex of heart;
	n/a
	More reference expression data
	n/a
Gene ontology
Molecular function	sequence-specific DNA binding; DNA binding; protein tyrosine kinase activity; RNA polymerase II transcription regulatory region sequence-specific DNA binding; protein-macromolecule adaptor activity; protein binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	cytosol; Golgi apparatus; nucleus; nucleoplasm; Golgi membrane; integral component of membrane; integral component of Golgi membrane; membrane;
Biological process	regulation of transcription by RNA polymerase II; multicellular organism development; retrograde transport, vesicle recycling within Golgi; positive regulation of dendrite morphogenesis; regulation of transcription, DNA-templated; negative regulation of transcription by RNA polymerase II; transcription, DNA-templated; peptidyl-tyrosine phosphorylation; Golgi vesicle transport; intra-Golgi vesicle-mediated transport;
	Sources:Amigo / QuickGO
Orthologs
	1523
	n/a
	ENSG00000257923
	n/a
	P39880; Q13948
	n/a
NM_001202543; NM_001202544; NM_001202545; NM_001202546; NM_001913;
	NM_181500; NM_181552
	n/a
NP_001189472; NP_001189473; NP_001189474; NP_001189475; NP_001904;
	NP_852477; NP_853530; NP_001189473.1; NP_001189474.1; NP_001189475.1; NP_001904.2; NP_852477.1
	n/a
	Wikidata
View/Edit Human

Cux1 (CUTL1, CDP, CDP/Cux) is a homeodomain protein that in humans is encoded by the CUX1 gene.^[3]^[4]^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000257923 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Scherer SW, Neufeld EJ, Lievens PM, Orkin SH, Kim J, Tsui LC (May 1993). "Regional localization of the CCAAT displacement protein gene (CUTL1) to 7q22 by analysis of somatic cell hybrids". Genomics. 15 (3): 695–6. doi:10.1006/geno.1993.1130. PMID 8468066.
^ Glöckner G, Scherer S, Schattevoy R, Boright A, Weber J, Tsui LC, Rosenthal A (December 1998). "Large-Scale Sequencing of Two Regions in Human Chromosome 7q22: Analysis of 650 kb of Genomic Sequence around the EPO and CUTL1 Loci Reveals 17 Genes". Genome Res. 8 (10): 1060–73. doi:10.1101/gr.8.10.1060. PMC 310788. PMID 9799793.
^ Oka T, Ungar D, Hughson FM, Krieger M (April 2004). "The COG and COPI Complexes Interact to Control the Abundance of GEARs, a Subset of Golgi Integral Membrane Proteins". Mol. Biol. Cell. 15 (5): 2423–35. doi:10.1091/mbc.E03-09-0699. PMC 404034. PMID 15004235.
^ "Entrez Gene: CUTL1 cut-like 1, CCAAT displacement protein (Drosophila)".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000257923 – Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8468066-3] Scherer SW, Neufeld EJ, Lievens PM, Orkin SH, Kim J, Tsui LC (May 1993). "Regional localization of the CCAAT displacement protein gene (CUTL1) to 7q22 by analysis of somatic cell hybrids". Genomics. 15 (3): 695–6. doi:10.1006/geno.1993.1130. PMID 8468066.

[pmid9799793-4] Glöckner G, Scherer S, Schattevoy R, Boright A, Weber J, Tsui LC, Rosenthal A (December 1998). "Large-Scale Sequencing of Two Regions in Human Chromosome 7q22: Analysis of 650 kb of Genomic Sequence around the EPO and CUTL1 Loci Reveals 17 Genes". Genome Res. 8 (10): 1060–73. doi:10.1101/gr.8.10.1060. PMC 310788. PMID 9799793.

[pmid15004235-5] Oka T, Ungar D, Hughson FM, Krieger M (April 2004). "The COG and COPI Complexes Interact to Control the Abundance of GEARs, a Subset of Golgi Integral Membrane Proteins". Mol. Biol. Cell. 15 (5): 2423–35. doi:10.1091/mbc.E03-09-0699. PMC 404034. PMID 15004235.

[entrez-6] "Entrez Gene: CUTL1 cut-like 1, CCAAT displacement protein (Drosophila)".

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