CYP2J2

CYP2J2
Identifiers
Aliases	CYP2J2, CPJ2, CYPIIJ2, cytochrome P450 family 2 subfamily J member 2
External IDs	OMIM: 601258; MGI: 1270148; HomoloGene: 68091; GeneCards: CYP2J2; OMA:CYP2J2 - orthologs
Gene location (Mouse) Chr. Chromosome 4 (mouse)[1] Band 4 C5|4 44.62 cM Start 96,404,375 bp[1] End 96,441,898 bp[1]
RNA expression pattern Bgee Human Mouse (ortholog) n/a Top expressed in saccule pyloric antrum epithelium of small intestine epithelium of stomach jejunum mucous cell of stomach otic vesicle nose olfactory epithelium duodenum BioGPS More reference expression data
Gene ontology Molecular function iron ion binding oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen metal ion binding arachidonic acid 14,15-epoxygenase activity heme binding oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen arachidonic acid 11,12-epoxygenase activity oxidoreductase activity aromatase activity linoleic acid epoxygenase activity monooxygenase activity arachidonic acid epoxygenase activity steroid hydroxylase activity Cellular component organelle membrane endoplasmic reticulum membrane membrane intracellular membrane-bounded organelle endoplasmic reticulum extracellular exosome cytoplasm Biological process linoleic acid metabolic process regulation of heart contraction epoxygenase P450 pathway icosanoid metabolic process xenobiotic metabolic process organic acid metabolic process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 1573 13110 Ensembl ENSG00000134716 ENSMUSG00000052914 UniProt P51589 O54750 RefSeq (mRNA) n/a NM_010008 RefSeq (protein) NP_000766 NP_034138 Location (UCSC) n/a Chr 4: 96.4 – 96.44 Mb PubMed search [2] [3]
Wikidata
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Cytochrome P450 2J2 (CYP2J2) is a protein that in humans is encoded by the CYP2J2 gene.^[4][5] CYP2J2 is a member of the cytochrome P450 superfamily of enzymes. The enzymes are oxygenases which catalyze many reactions involved in the metabolism of drugs and other xenobiotics) as well as in the synthesis of cholesterol, steroids and other lipids.