Calbindin

calbindin 1, 28kDa
NMR solution structure of Ca2+-loaded calbindin D28K.[1]
Identifiers
SymbolCALB1
Alt. symbolsCALB
NCBI gene793
HGNC1434
OMIM114050
RefSeqNM_004929
UniProtP05937
Other data
LocusChr. 8 p11
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StructuresSwiss-model
DomainsInterPro
calbindin 2, 29kDa (calretinin)
Identifiers
SymbolCALB2
NCBI gene794
HGNC1435
OMIM114051
RefSeqNM_001740
UniProtP22676
Other data
LocusChr. 16 q22.1
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StructuresSwiss-model
DomainsInterPro

Calbindins are three different calcium-binding proteins: calbindin, calretinin and S100G. They were originally described as vitamin D-dependent calcium-binding proteins in the intestine and kidney of chicks and mammals. They are now classified in different subfamilies as they differ in the number of Ca2+ binding EF hands.

  1. ^ PDB: 2G9B​; Kojetin DJ, Venters RA, Kordys DR, Thompson RJ, Kumar R, Cavanagh J (July 2006). "Structure, binding interface and hydrophobic transitions of Ca2+-loaded calbindin-D(28K)". Nature Structural & Molecular Biology. 13 (7): 641–7. doi:10.1038/nsmb1112. PMID 16799559. S2CID 29426332.