Capnocytophaga canimorsus

Capnocytophaga canimorsus
Scientific classification Edit this classification
Domain: Bacteria
Phylum: Bacteroidota
Class: Flavobacteriia
Order: Flavobacteriales
Family: Flavobacteriaceae
Genus: Capnocytophaga
Species:
C. canimorsus
Binomial name
Capnocytophaga canimorsus
Brenner et al. 1989

Capnocytophaga canimorsus is a fastidious, slow-growing, Gram-negative rod of the genus Capnocytophaga.[1][2] It is a commensal bacterium in the normal gingival microbiota of canine and feline species, but can cause illness in humans. Transmission may occur through bites, licks, or even close proximity with animals.[3] C. canimorsus generally has low virulence in healthy individuals,[4] but has been observed to cause severe, even grave, illness in persons with pre-existing conditions.[5] The pathogenesis of C. canimorsus is still largely unknown, but increased clinical diagnoses have fostered an interest in the bacillus. Treatment with antibiotics is effective in most cases, but the most important yet basic diagnostic tool available to clinicians remains the knowledge of recent exposure to canines or felines.[3]

  1. ^ Pers, C.; Gahrn-Hansen, B.; Frederiksen, W. (1996-07-01). "Capnocytophaga canimorsus Septicemia in Denmark, 1982-1995: Review of 39 Cases". Clinical Infectious Diseases. 23 (1): 71–75. doi:10.1093/clinids/23.1.71. ISSN 1058-4838. PMID 8816132.
  2. ^ Brenner, D J; Hollis, D G; Fanning, G R; Weaver, R E (1989). "Capnocytophaga canimorsus sp. nov. (formerly CDC group DF-2), a cause of septicemia following dog bite, and C. cynodegmi sp. nov., a cause of localized wound infection following dog bite". Journal of Clinical Microbiology. 27 (2): 231–235. doi:10.1128/jcm.27.2.231-235.1989. ISSN 0095-1137. PMC 267282. PMID 2915017.
  3. ^ a b Fischer, L J; Weyant, R S; White, E H; Quinn, F D (1995). "Intracellular multiplication and toxic destruction of cultured macrophages by Capnocytophaga canimorsus". Infection and Immunity. 63 (9): 3484–3490. doi:10.1128/iai.63.9.3484-3490.1995. ISSN 0019-9567. PMC 173481. PMID 7642281.
  4. ^ Lion, C.; Escande, F.; Burdin, J.C. (1996). "Capnocytophaga canimorsus infections in human: Review of the literature and cases report". European Journal of Epidemiology. 12 (5): 521–533. doi:10.1007/BF00144007. PMID 8905316. S2CID 22408402.
  5. ^ Le Moal G; Landron C; Grollier G; Robert R; Burucoa C (2003). "Meningitis Due to Capnocytophaga canimorsus after Receipt of a Dog Bite: Case Report and Review of the Literature". Clin Infect Dis. 36 (3): e42–46. doi:10.1086/345477. PMID 12539089.