Caylee is a given name. Notable people with the name include:
- Caylee Anthony (2005–2008), American two-year old murder victim
- Caylee Cowan, actress in the 2019 American film Sunrise in Heaven
- Caylee Hammack (born 1994), American country music singer and songwriter
- Caylee Turner, ring name of Christina Crawford (born 1988), American professional wrestler
- Caylee Watson (born 1994), United States Virgin Islands swimmer