CboK7

CboK7
Identifiers
Symbol?
UniProtC0HM78
Search for
StructuresSwiss-model
DomainsInterPro
CboK7
Identifiers
3D model (JSmol)
  • InChI=1S/C189H302N52O52S7/c1-15-101(10)152(237-172(275)126(78-105-38-17-16-18-39-105)226-183(286)149(201)103(12)243)185(288)227-129(83-143(200)249)173(276)235-150(99(6)7)184(287)217-116(45-24-32-69-195)162(265)233-137-95-300-296-91-133-175(278)215-120(63-75-294-14)165(268)223-128(82-142(199)248)156(259)204-87-145(251)208-111(40-19-27-64-190)157(260)229-132-90-295-297-92-134(232-164(267)119(59-61-141(198)247)214-158(261)115(44-23-31-68-194)216-181(284)139-49-37-74-241(139)188(291)131(89-242)228-186(289)153(104(13)244)238-179(137)282)177(280)220-122(76-97(2)3)168(271)218-121(47-26-34-71-197)187(290)240-73-36-50-140(240)182(285)234-136(94-299-298-93-135(231-161(264)114(213-174(132)277)43-22-30-67-193)178(281)222-125(80-107-53-57-110(246)58-54-107)170(273)211-117(46-25-33-70-196)166(269)236-151(100(8)9)189(292)293)176(279)212-112(41-20-28-65-191)159(262)224-130(84-148(255)256)171(274)219-123(77-98(4)5)169(272)221-124(79-106-51-55-109(245)56-52-106)155(258)205-88-146(252)239-72-35-48-138(239)180(283)225-127(81-108-85-202-96-206-108)167(270)207-102(11)154(257)203-86-144(250)209-118(60-62-147(253)254)163(266)210-113(160(263)230-133)42-21-29-66-192/h16-18,38-39,51-58,85,96-104,111-140,149-153,242-246H,15,19-37,40-50,59-84,86-95,190-197,201H2,1-14H3,(H2,198,247)(H2,199,248)(H2,200,249)(H,202,206)(H,203,257)(H,204,259)(H,205,258)(H,207,270)(H,208,251)(H,209,250)(H,210,266)(H,211,273)(H,212,279)(H,213,277)(H,214,261)(H,215,278)(H,216,284)(H,217,287)(H,218,271)(H,219,274)(H,220,280)(H,221,272)(H,222,281)(H,223,268)(H,224,262)(H,225,283)(H,226,286)(H,227,288)(H,228,289)(H,229,260)(H,230,263)(H,231,264)(H,232,267)(H,233,265)(H,234,285)(H,235,276)(H,236,269)(H,237,275)(H,238,282)(H,253,254)(H,255,256)(H,292,293)/t101-,102-,103+,104+,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,149-,150-,151-,152-,153-/m0/s1
    Key: WUMCQARMGKDNOT-FIQXMJQTSA-N
  • N[C@@]([H])([C@]([H])(O)C)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])([C@]([H])(CC)C)C(=O)N[C@@]([H])(CC(=O)N)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CS2)C(=O)N[C@@]([H])([C@]([H])(O)C)C(=O)N[C@@]([H])(CO)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CCC(=O)N)C(=O)N[C@@]([H])(CS3)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CCCCN)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CS4)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CC(=O)O)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)NCC(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CC1=CN=C-N1)C(=O)N[C@@]([H])(C)C(=O)NCC(=O)N[C@@]([H])(CCC(=O)O)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CS2)C(=O)N[C@@]([H])(CCSC)C(=O)N[C@@]([H])(CC(=O)N)C(=O)NCC(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CS3)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CS4)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(C(C)C)C(=O)O
Properties
C189H302N52O52S7
Molar mass 4359.23 g·mol−1
Related compounds
Related compounds
 CboK3, CboK4
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

CboK7, also known as α-KTx 2.24, is a toxin produced by a species of scorpion, Centruroides bonito. It blocks voltage-gated K+ channels, with the highest affinity for Kv1.2 channels.