Clinical data | |
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Other names | CPZ; CTZ |
Routes of administration | Oral[1] |
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Chemical and physical data | |
Formula | C22H28N2O3 |
Molar mass | 368.477 g·mol−1 |
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Centpropazine (CPZ, CTZ) is an experimental antidepressant which was under development for the treatment major depressive disorder in India but was never marketed.[1][2][3] It is described as having imipramine-like clinical effects, reversing reserpine-induced effects in animals, and potentiating amphetamine-induced effects in animals.[3] The mechanism of action of centpropazine is unknown.[4] The drug reached phase 3 clinical trials prior to the discontinuation of its development.[1] It was first described in the scientific literature by 1980.[3][5]