Cerebral amyloid angiopathy

Cerebral amyloid angiopathy
Other namesCongophilic angiopathy[1]
Micrograph of cerebral amyloid angiopathy using congo red stain
SpecialtyNeurology Edit this on Wikidata
CausesCause of CAA is unknown[2]
Diagnostic methodPET scan, CT scan[2]
TreatmentManagement can be physical, occupational, or speech therapy.[2]

Cerebral amyloid angiopathy (CAA) is a form of angiopathy in which amyloid beta peptide deposits in the walls of small to medium blood vessels of the central nervous system and meninges.[2][3] The term congophilic is sometimes used because the presence of the abnormal aggregations of amyloid can be demonstrated by microscopic examination of brain tissue after staining with Congo red. The amyloid material is only found in the brain and as such the disease is not related to other forms of amyloidosis.[4]

  1. ^ Exley C, Esiri MM (July 2006). "Severe cerebral congophilic angiopathy coincident with increased brain aluminium in a resident of Camelford, Cornwall, UK". J. Neurol. Neurosurg. Psychiatry. 77 (7): 877–9. doi:10.1136/jnnp.2005.086553. PMC 2117501. PMID 16627535.
  2. ^ a b c d "Cerebral amyloid angiopathy: MedlinePlus Medical Encyclopedia". www.nlm.nih.gov. Retrieved 2015-05-27.
  3. ^ "UpToDate". www.uptodate.com. Retrieved 2019-08-17.
  4. ^ Newfoundland, FRCP William Pryse-Phillips MD, FRCP(C) Faculty of Medicine Health Sciences Centre Memorial University of Newfoundland St John's (2009-05-06). Companion to Clinical Neurology. Oxford University Press, USA. ISBN 9780199710041.{{cite book}}: CS1 maint: multiple names: authors list (link)