Charles John Seghers | |
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| Born | 26 December 1839 Ghent, Belgium |
| Died | 28 November 1886 (aged 46) Near Nulato, District of Alaska |
| Occupation | Catholic missionary bishop |
Charles John Seghers (also written as Charles-Jean Seghers; 26 December 1839 – 28 November 1886) was a Belgian clergyman and missionary bishop. He is considered to be the founder of the Alaska Mission.