Chemerin

RARRES2
Identifiers
Aliases	RARRES2, HP10433, TIG2, Chemerin, retinoic acid receptor responder 2
External IDs	OMIM: 601973; MGI: 1918910; HomoloGene: 2167; GeneCards: RARRES2; OMA:RARRES2 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	150,341,662 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	48,549,723 bp
RNA expression pattern
	Top expressed in
	right adrenal cortex; ; left adrenal cortex; ; right lobe of liver; ; left ovary; ; right ovary; ; canal of the cervix; ; left uterine tube; ; body of pancreas; ; body of uterus; ; tibial nerve;
	Top expressed in
	left lobe of liver; ; ascending aorta; ; white adipose tissue; ; decidua; ; lactiferous gland; ; aortic valve; ; uterus; ; gallbladder; ; right lung lobe; ; umbilical cord;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; signaling receptor binding;
Cellular component	extracellular matrix; platelet dense granule lumen; extracellular region; extracellular space; collagen-containing extracellular matrix;
Biological process	in utero embryonic development; embryonic digestive tract development; positive regulation of macrophage chemotaxis; chemotaxis; retinoid metabolic process; cell differentiation; inflammatory response; regulation of lipid catabolic process; platelet degranulation; positive regulation of protein phosphorylation; positive regulation of fat cell differentiation; positive regulation of chemotaxis; innate immune response; insulin receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	5919
	71660
	ENSG00000106538
	ENSMUSG00000009281
	Q99969
	Q9DD06
	NM_002889
	NM_027852; NM_001347167; NM_001347168
	NP_002880; NP_002880.1
	NP_001334096; NP_001334097; NP_082128
	Wikidata
View/Edit Human	View/Edit Mouse

Chemerin, also known as retinoic acid receptor responder protein 2 (RARRES2), tazarotene-induced gene 2 protein (TIG2), or RAR-responsive protein TIG2 is a protein that in humans is encoded by the RARRES2 gene.^[5]^[6]^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000106538 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000009281 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Duvic M, Nagpal S, Asano AT, Chandraratna RA (Sep 1997). "Molecular mechanisms of tazarotene action in psoriasis". J. Am. Acad. Dermatol. 37 (2 Pt 3): S18–24. doi:10.1016/s0190-9622(97)80396-9. PMID 9270552.
^ Roh SG, Song SH, Choi KC, Katoh K, Wittamer V, Parmentier M, Sasaki S (Sep 2007). "Chemerin--a new adipokine that modulates adipogenesis via its own receptor". Biochem. Biophys. Res. Commun. 362 (4): 1013–8. doi:10.1016/j.bbrc.2007.08.104. hdl:10091/618. PMID 17767914.
^ "Entrez Gene: RARRES2 retinoic acid receptor responder (tazarotene induced) 2".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000106538 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000009281 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9270552-5] Duvic M, Nagpal S, Asano AT, Chandraratna RA (Sep 1997). "Molecular mechanisms of tazarotene action in psoriasis". J. Am. Acad. Dermatol. 37 (2 Pt 3): S18–24. doi:10.1016/s0190-9622(97)80396-9. PMID 9270552.

[pmid17767914-6] Roh SG, Song SH, Choi KC, Katoh K, Wittamer V, Parmentier M, Sasaki S (Sep 2007). "Chemerin--a new adipokine that modulates adipogenesis via its own receptor". Biochem. Biophys. Res. Commun. 362 (4): 1013–8. doi:10.1016/j.bbrc.2007.08.104. hdl:10091/618. PMID 17767914.

[entrez-7] "Entrez Gene: RARRES2 retinoic acid receptor responder (tazarotene induced) 2".

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