The Cherokee Nuclear Power Plant is an incomplete energy project 10 miles (16 km) outside Gaffney, South Carolina, United States. In the early 1970s, Duke Power started construction on a three-reactor nuclear power plant at the site. However, the project stalled due to economic problems by the early 1980s, leading to the project's eventual abandonment. In 1987, the power plant was the site of an underwater film studio built by Hollywood director James Cameron, for the film The Abyss.
On December 13, 2007, Duke Energy filed an application with the U.S. Nuclear Regulatory Commission to construct a new $5–6 billion two-unit nuclear power plant at William States Lee III Nuclear Generating Station near the Cherokee Nuclear Power Plant site. In November 2008, the estimated cost to complete the project was raised to $11 billion (equivalent to $15.6 billion in 2023).