Chlorobenzene

Chlorobenzene
Chlorobenzene
Chlorobenzene
Chlorobenzene
Chlorobenzene
Names
Preferred IUPAC name
Chlorobenzene
Other names
Phenyl chloride, monochlorobenzene[1]
Identifiers
3D model (JSmol)
3DMet
Abbreviations PhCl
605632
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard 100.003.299 Edit this at Wikidata
EC Number
  • 203-628-5
26704
KEGG
RTECS number
  • CZ0175000
UNII
UN number 1134
  • InChI=1S/C6H5Cl/c7-6-4-2-1-3-5-6/h1-5H checkY
    Key: MVPPADPHJFYWMZ-UHFFFAOYSA-N checkY
  • InChI=1/C6H5Cl/c7-6-4-2-1-3-5-6/h1-5H
    Key: MVPPADPHJFYWMZ-UHFFFAOYAG
  • Clc1ccccc1
Properties
C6H5Cl
Molar mass 112.56 g/mol
Appearance colorless liquid
Odor almond-like[2]
Density 1.11 g/cm3, liquid
Melting point −45.58 °C (−50.04 °F; 227.57 K)
Boiling point 131.70 °C (269.06 °F; 404.85 K)
0.5 g l−1 in water at 20 °C
Solubility in other solvents soluble in most organic solvents
Vapor pressure 9 mmHg[2]
−69.97·10−6 cm3/mol
1.52138
Viscosity 0.7232
Hazards
Occupational safety and health (OHS/OSH):
Main hazards
 Low to moderate hazard[3]
GHS labelling:
GHS02: Flammable GHS07: Exclamation mark GHS09: Environmental hazard
Warning
H226, H302, H305, H315, H332, H411
P210, P233, P240, P241, P242, P243, P261, P264, P271, P273, P280, P302+P352, P303+P361+P353, P304+P312, P304+P340, P312, P321, P332+P313, P362, P370+P378, P391, P403+P235, P501
NFPA 704 (fire diamond)
NFPA 704 four-colored diamondHealth 2: Intense or continued but not chronic exposure could cause temporary incapacitation or possible residual injury. E.g. chloroformFlammability 3: Liquids and solids that can be ignited under almost all ambient temperature conditions. Flash point between 23 and 38 °C (73 and 100 °F). E.g. gasolineInstability 0: Normally stable, even under fire exposure conditions, and is not reactive with water. E.g. liquid nitrogenSpecial hazards (white): no code
2
3
0
Flash point 29 °C (84 °F; 302 K)
Explosive limits 1.3%-9.6%[2]
Lethal dose or concentration (LD, LC):
2290 mg/kg (rat, oral)

590 mg/kg (mouse, orally)[4]
2250 mg/kg (rabbit, oral)
2300 mg/kg (mouse, oral)
2250 mg/kg (guinea pig, oral)[5]

8000 ppm (cat, 3 hr)[5]
NIOSH (US health exposure limits):
PEL (Permissible)
 TWA 75 ppm (350 mg/m3)[2]
REL (Recommended)
 none[2]
IDLH (Immediate danger)
 1000 ppm[2]
Related compounds
Related Halobenzenes
 Fluorobenzene
Bromobenzene
Iodobenzene
Related compounds
 benzene
1,4-dichlorobenzene
Supplementary data page
Chlorobenzene (data page)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
checkY verify (what is checkY☒N ?)

Chlorobenzene (abbreviated PhCl) is an aryl chloride and the simplest of the chlorobenzenes, consisting of a benzene ring substituted with one chlorine atom. Its chemical formula is C6H5Cl. This colorless, flammable liquid is a common solvent and a widely used intermediate in the manufacture of other chemicals.[6]

  1. ^ Pubchem. "Chlorobenzene". pubchem.ncbi.nlm.nih.gov. Retrieved 2022-08-21.
  2. ^ a b c d e f NIOSH Pocket Guide to Chemical Hazards. "#0121". National Institute for Occupational Safety and Health (NIOSH).
  3. ^ Chlorobenzene toxicity
  4. ^ Chlorobenzene: LD50
  5. ^ a b "Chlorobenzene". Immediately Dangerous to Life or Health Concentrations (IDLH). National Institute for Occupational Safety and Health (NIOSH).
  6. ^ Cite error: The named reference ClPh was invoked but never defined (see the help page).