| Christina of Lorraine | |
|---|---|
 Portrait of Christine, 1588 | |
| Grand Duchess consort of Tuscany | |
| Tenure | 3 May 1589 – 17 February 1609 |
| Born | Christine de Lorraine 16 August 1565 Ducal Palace of Nancy, Lorraine |
| Died | 19 December 1637 (aged 72) Palazzo Pitti, Florence, Tuscany |
| Burial | |
| Spouse | Ferdinando I, Grand Duke of Tuscany |
| Issue | Cosimo II, Grand Duke of Tuscany Maria Maddalena de' Medici Catherine, Governor of Siena Carlo de' Medici Claudia, Archduchess of Austria |
| House | House of Lorraine (by birth) House of Medici (by marriage) |
| Father | Charles III, Duke of Lorraine |
| Mother | Claude of Valois |
Christina of Lorraine (French: Christine de Lorraine, Italian: Cristina di Lorena) (16 August 1565 – 19 December 1637) was a noblewoman of the House of Lorraine who became a Grand Duchess of Tuscany by marriage. She served as Regent of Tuscany jointly with her daughter-in-law during the minority of her grandson from 1621 to 1628.