Chromium(III) picolinate

Chromium(III) picolinate
Skeletal formula of chromium(III) picolinate
Watch glass with two grams of chromium(III) picolinate]]
Names
IUPAC name
Tris(picolinate)chromium(III)
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
ECHA InfoCard 100.131.423 Edit this at Wikidata
UNII
  • InChI=1S/3C6H5NO2.Cr/c3*8-6(9)5-3-1-2-4-7-5;/h3*1-4H,(H,8,9);/q;;;+3/p-3 checkY
    Key: CBDQOLKNTOMMTL-UHFFFAOYSA-K checkY
  • InChI=1/3C6H5NO2.Cr/c3*8-6(9)5-3-1-2-4-7-5;/h3*1-4H,(H,8,9);/q;;;+3/p-3
    Key: CBDQOLKNTOMMTL-DFZHHIFOAM
  • ionic form: c1ccnc(c1)C(=O)[O-].c1ccnc(c1)C(=O)[O-].c1ccnc(c1)C(=O)[O-].[Cr+3]
  • coordination form: c0ccc[n+]1c0C(=O)O[Cr-3]123(OC(=O)c0[n+]2cccc0)OC(=O)c0[n+]3cccc0
Properties
C16H12CrN3O6
Molar mass 394.283 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Chromium(III) picolinate (also trivalent chromium) is a chemical compound with the formula Cr(C5H4N(CO2))3, commonly abbreviated as CrPic3. It is a bright-red coordination compound derived from chromium(III) and picolinic acid.

Trivalent chromium occurs naturally in many foods and is one of several forms of chromium sold as a dietary supplement intended to correct chromium deficiency. However, there is no evidence of chromium deficiency in healthy people and no medical symptoms of chromium deficiency exist.[1][2] Supplementation with trivalent chromium does not prevent or treat obesity, impaired prediabetes condition, type 2 diabetes or metabolic syndrome, and is not considered effective for maintaining or losing body weight.[1][2]

Although daily doses of trivalent chromium up to 1,000 μg are considered to be safe, some adverse effects have been reported, and there is no clinical evidence that chromium supplementation provides any health benefit.[1][2]

  1. ^ a b c "Chromium". Office of Dietary Supplements, US National Institutes of Health. 2 June 2022. Retrieved 17 October 2024.
  2. ^ a b c "Chromium". Micronutrient Information Center, Linus Pauling Institute, Oregon State University, Corvallis. January 2024. Retrieved 17 October 2024.