Chromosome 15

Chromosome 15
Human chromosome 15 pair after G-banding.
One is from mother, one is from father.
Chromosome 15 pair
in human male karyogram.
Features
Length (bp)99,753,195 bp
(CHM13)
No. of genes561 (CCDS)[1]
TypeAutosome
Centromere positionAcrocentric[2]
(19.0 Mbp[3])
Complete gene lists
CCDSGene list
HGNCGene list
UniProtGene list
NCBIGene list
External map viewers
EnsemblChromosome 15
EntrezChromosome 15
NCBIChromosome 15
UCSCChromosome 15
Full DNA sequences
RefSeqNC_000015 (FASTA)
GenBankCM000677 (FASTA)

Chromosome 15 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome 15 spans about 99.7 million base pairs (the building material of DNA) and represents between 3% and 3.5% of the total DNA in cells. Chromosome 15 is an acrocentric chromosome, with a very small short arm (the "p" arm, for "petite"), which contains few protein coding genes among its 19 million base pairs. It has a larger long arm (the "q" arm) that is gene rich, spanning about 83 million base pairs.

The human leukocyte antigen gene for β2-microglobulin is found on chromosome 15, as well as the FBN1 gene, coding for both fibrillin-1 (a protein critical to the proper functioning of connective tissue), and asprosin (a small protein produced from part of the transcribed FBN1 gene mRNA), which is involved in fat metabolism.

  1. ^ Cite error: The named reference CCDS was invoked but never defined (see the help page).
  2. ^ Tom Strachan; Andrew Read (2 April 2010). Human Molecular Genetics. Garland Science. p. 45. ISBN 978-1-136-84407-2.
  3. ^ Genome Decoration Page, NCBI. Ideogram data for Homo sapience (850 bphs, Assembly GRCh38.p3). Last update 2014-06-03. Retrieved 2017-04-26.