| Chromosome 5 | |
|---|---|
 Human chromosome 5 pair after G-banding. One is from mother, one is from father. | |
 Chromosome 5 pair in human male karyogram. | |
| Features | |
| Length (bp) | 182,045,439 bp (CHM13) |
| No. of genes | 839 (CCDS)[1] |
| Type | Autosome |
| Centromere position | Submetacentric[2] (48.8 Mbp[3]) |
| Complete gene lists | |
| CCDS | Gene list |
| HGNC | Gene list |
| UniProt | Gene list |
| NCBI | Gene list |
| External map viewers | |
| Ensembl | Chromosome 5 |
| Entrez | Chromosome 5 |
| NCBI | Chromosome 5 |
| UCSC | Chromosome 5 |
| Full DNA sequences | |
| RefSeq | NC_000005 (FASTA) |
| GenBank | CM000667 (FASTA) |
Chromosome 5 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome 5 spans about 182 million base pairs (the building blocks of DNA) and represents almost 6% of the total DNA in cells. Chromosome 5 is the 5th largest human chromosome, yet has one of the lowest gene densities. This is partially explained by numerous gene-poor regions that display a remarkable degree of non-coding and syntenic conservation with non-mammalian vertebrates, suggesting they are functionally constrained.[4]
Because chromosome 5 is responsible for many forms of growth and development (cell divisions) changes may cause cancers. One example would be acute myeloid leukemia (AML).[5]
- ^ Cite error: The named reference
CCDSwas invoked but never defined (see the help page). - ^ Tom Strachan, Andrew Read (2 April 2010). Human Molecular Genetics. Garland Science. p. 45. ISBN 978-1-136-84407-2.
- ^ Genome Decoration Page, NCBI. Ideogram data for Homo sapience (850 bphs, Assembly GRCh38.p3). Last update 2014-06-03. Retrieved 2017-04-26.
- ^ "Home - Homo sapiens". Archived from the original on 2015-04-02. Retrieved 2007-02-07.
- ^ "Chromosome 5". Genetics Home Reference. Lister Hill National Center for Biomedical Communications. U.S. National Library of Medicine. December 2014.