Chrysin

Chrysin
Chrysin
Ball-and-stick model of chrysin
Names
IUPAC name
5,7-Dihydroxyflavone
Systematic IUPAC name
5,7-Dihydroxy-2-phenyl-4H-1-benzopyran-4-one
Other names
NP-005901; Galangin flavanone
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard 100.006.864 Edit this at Wikidata
KEGG
UNII
  • InChI=1S/C15H10O4/c16-10-6-11(17)15-12(18)8-13(19-14(15)7-10)9-4-2-1-3-5-9/h1-8,16-17H checkY
    Key: RTIXKCRFFJGDFG-UHFFFAOYSA-N checkY
  • InChI=1/C15H10O4/c16-10-6-11(17)15-12(18)8-13 (19-14(15)7-10)9-4-2-1-3-5-9/h1-8,16-17H
    Key: RTIXKCRFFJGDFG-UHFFFAOYAO
  • O=C\1c3c(O/C(=C/1)c2ccccc2)cc(O)cc3O
Properties
C15H10O4
Molar mass 254.241 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)

Chrysin, also called 5,7-dihydroxyflavone,[1] is a flavone found in honey, propolis, the passion flowers, Passiflora caerulea and Passiflora incarnata, and in Oroxylum indicum.[2] It is extracted from various plants, such as the blue passion flower (Passiflora caerulea).[1] Following oral intake by humans, chrysin has low bioavailability and rapid excretion.[1] It is under basic research to evaluate its safety and potential biological effects.[1]

Chrysin is an ingredient in dietary supplements.[3] As of 2016, there was no clinical use of chrysin,[1] and no evidence for its effect on testosterone levels.[4] In 2016, the US Food and Drug Administration did not recommend chrysin be included on the list of bulk drug substances that can be used in compounding under section 503A of the Federal Food, Drug, and Cosmetic Act.[5]

  1. ^ a b c d e Cite error: The named reference PubChem was invoked but never defined (see the help page).
  2. ^ Cite error: The named reference Brahmachari2017 was invoked but never defined (see the help page).
  3. ^ FDA 2016, p. 3.
  4. ^ FDA 2016, p. 8.
  5. ^ FDA 2016, p. 13.