Chuan He

The native form of this personal name is He Chuan. This article uses Western name order when mentioning individuals.
Chuan He
Chuan He
Born1972
Guizhou, China
Alma materUniversity of Science and Technology of China (B.S.)
Massachusetts Institute of Technology (Ph.D.)
Known forEpigenetics, DNA Methylation
AwardsSearle Scholar Award (2003)
Beckman Young Investigators Award (2005)
Paul Marks Prize for Cancer Research (2017)
ACS Chemical Biology Lectureship (2019)
Wolf Prize in Chemistry (2023)
Scientific career
FieldsChemical Biology, Genetics
InstitutionsUniversity of Chicago
Doctoral advisorStephen J. Lippard
Other academic advisorsGregory L. Verdine

Chuan He (Chinese: 何川) is a Chinese-American chemical biologist. He currently serves as the John T. Wilson Distinguished Service Professor at the University of Chicago, and an Investigator of the Howard Hughes Medical Institute.[1] He is best known for his work in discovering and deciphering reversible RNA methylation in post-transcriptional gene expression regulation.[2] He was awarded the 2023 Wolf Prize in Chemistry for his work in discovering and deciphering reversible RNA methylation in post-transcriptional gene expression regulation in addition to his contributions to the invention of TAB-seq, a biochemical method that can map 5-hydroxymethylcytosine (5hmC) at base-resolution genome-wide, as well as hmC-Seal, a method that covalently labels 5hmC for its detection and profiling.[2]

  1. ^ Cite error: The named reference hhmi was invoked but never defined (see the help page).
  2. ^ a b He C (November 2010). "Grand Challenge Commentary: RNA epigenetics?". Nat. Chem. Biol. 6 (12): 863–865. doi:10.1038/nchembio.482. PMID 21079590.