Ciclopirox

Ciclopirox
Clinical data
Trade namesMany[1]
Other namesLoprox, CPX
AHFS/Drugs.comMicromedex Detailed Consumer Information
MedlinePlusa604021
Pregnancy
category
  • B
Routes of
administration
Topical
ATC code
Legal status
Legal status
Pharmacokinetic data
Bioavailability<5% with prolonged use
Protein binding94 to 97%
Elimination half-life1.7 hours
Identifiers
  • 6-cyclohexyl-1-hydroxy-4-methylpyridin-2(1H)-one
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.045.056 Edit this at Wikidata
Chemical and physical data
FormulaC12H17NO2
Molar mass207.273 g·mol−1
3D model (JSmol)
  • O=C1/C=C(\C=C(/N1O)C2CCCCC2)C
  • InChI=1S/C12H17NO2/c1-9-7-11(13(15)12(14)8-9)10-5-3-2-4-6-10/h7-8,10,15H,2-6H2,1H3 checkY
  • Key:SCKYRAXSEDYPSA-UHFFFAOYSA-N checkY
  (verify)

Ciclopirox is a synthetic antifungal agent for topical dermatologic treatment of superficial mycoses. It is most useful against tinea versicolor. It is often used clinically as ciclopirox olamine, the olamine salt of ciclopirox.

In 2021, it was the 271st most commonly prescribed medication in the United States, with more than 900,000 prescriptions.[2][3]

  1. ^ Cite error: The named reference brands was invoked but never defined (see the help page).
  2. ^ "The Top 300 of 2021". ClinCalc. Archived from the original on 15 January 2024. Retrieved 14 January 2024.
  3. ^ "Ciclopirox - Drug Usage Statistics". ClinCalc. Archived from the original on 15 January 2024. Retrieved 14 January 2024.