Citicoline

Citicoline
Clinical data
Trade namesNeurocoline
Other namesCytidine diphosphate choline
AHFS/Drugs.comInternational Drug Names
Routes of
administration
oral
ATC code
Legal status
Legal status
Pharmacokinetic data
Bioavailability90% oral
Excretionrespiration (as CO2) and urine
Identifiers
  • 5'-O-[hydroxy({hydroxy[2-(trimethylammonio)ethoxy]
    phosphoryl}oxy)phosphoryl]cytidine
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.012.346 Edit this at Wikidata
Chemical and physical data
FormulaC14H27N4O11P2+
Molar mass489.335 g·mol−1
3D model (JSmol)
  • C[N+](C)(C)CCOP(=O)([O-])OP(=O)(O)OC[C@@H]1[C@@H](O)[C@@H](O)[C@@H](O1)N2C=CC(N)=NC2=O
  • InChI=1S/C14H26N4O11P2/c1-18(2,3)6-7-26-30(22,23)29-31(24,25)27-8-9-11(19)12(20)13(28-9)17-5-4-10(15)16-14(17)21/h4-5,9,11-13,19-20H,6-8H2,1-3H3,(H3-,15,16,21,22,23,24,25)/t9-,11-,12-,13-/m1/s1 ☒N
  • Key:RZZPDXZPRHQOCG-OJAKKHQRSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

Citicoline (INN), also known as cytidine diphosphate-choline (CDP-choline) or cytidine 5'-diphosphocholine is an intermediate in the generation of phosphatidylcholine from choline, a common biochemical process in cell membranes. Citicoline is naturally occurring in the cells of human and animal tissue, in particular the organs.