Cln3

This article is about the budding yeast cyclin. For other uses, see Cln3 (disambiguation).
G1/S-specific cyclin CLN3
Identifiers
OrganismS. cerevisiae (Baker's yeast)
SymbolCLN3
Alt. symbolsYAL040C, WHI1, DAF1, FUN10
Entrez851191
RefSeq (mRNA)NM_001178185
RefSeq (Prot)NP_009360
UniProtP13365
Other data
Chromosome1: 0.07 - 0.07 Mb
Search for
StructuresSwiss-model
DomainsInterPro

G1/S-specific cyclin Cln3 is a protein that is encoded by the CLN3 gene. The Cln3 protein is a budding yeast G1 cyclin that controls the timing of Start, the point of commitment to a mitotic cell cycle. It is an upstream regulator of the other G1 cyclins,[1] and it is thought to be the key regulator linking cell growth to cell cycle progression.[2][3] It is a 65 kD, unstable protein;[4] like other cyclins, it functions by binding and activating cyclin-dependent kinase (CDK).[5]

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