Coding region

The coding region of a gene, also known as the coding sequence (CDS), is the portion of a gene's DNA or RNA that codes for a protein.[1] Studying the length, composition, regulation, splicing, structures, and functions of coding regions compared to non-coding regions over different species and time periods can provide a significant amount of important information regarding gene organization and evolution of prokaryotes and eukaryotes.[2] This can further assist in mapping the human genome and developing gene therapy.[3]

  1. ^ Twyman, Richard (1 August 2003). "Gene Structure". The Wellcome Trust. Archived from the original on 28 March 2007. Retrieved 6 April 2003.
  2. ^ Höglund M, Säll T, Röhme D (February 1990). "On the origin of coding sequences from random open reading frames". Journal of Molecular Evolution. 30 (2): 104–108. Bibcode:1990JMolE..30..104H. doi:10.1007/bf02099936. ISSN 0022-2844. S2CID 5978109.
  3. ^ Sakharkar MK, Chow VT, Kangueane P (2004). "Distributions of exons and introns in the human genome". In Silico Biology. 4 (4): 387–93. PMID 15217358.