Contig

This article is about contig in DNA sequencing. For the contig defragmentation program, see Contig (defragmentation utility).

A contig (from contiguous) is a set of overlapping DNA segments that together represent a consensus region of DNA.[1] In bottom-up sequencing projects, a contig refers to overlapping sequence data (reads);[2] in top-down sequencing projects, contig refers to the overlapping clones that form a physical map of the genome that is used to guide sequencing and assembly.[3] Contigs can thus refer both to overlapping DNA sequences and to overlapping physical segments (fragments) contained in clones depending on the context.

  1. ^ Gregory, S. Contig Assembly. Encyclopedia of Life Sciences, 2005.
  2. ^ Gibson, Greg; Muse, Spencer V. (2009). A Primer of Genome Science (3rd ed.). Sinauer Associates. p. 84. ISBN 978-0-878-93236-8.
  3. ^ Dear, P. H. Genome Mapping. Encyclopedia of Life Sciences, 2005. doi:10.1038/npg.els.0005353.