Control region may refer to:
- mtDNA control region, an area of the mitochondrial genome which is non-coding DNA.
- Locus control region, a long-range cis-regulatory element that enhances expression of linked genes at ectopic chromatin sites.
- Internal control region, a sequence of DNA located with the coding region of eukaryotic genes that binds regulatory elements such as activators or repressors.
- Processor Control Region, a Windows kernel mode data structure that contains information about the current processor.
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