Curcuminoid

Curcumin
Demethoxycurcumin
Bisdemethoxycurcumin

A curcuminoid is a linear diarylheptanoid, a relatively small class of plant secondary metabolites that includes curcumin, demethoxycurcumin, and bisdemethoxycurcumin, all isolated from turmeric (curcuma longa). These compounds are natural phenols and produce a pronounced yellow color that is often used to color foods and medicines. Curcumin is obtained from the root of turmeric.

Curcuminoids are soluble in dimethyl sulfoxide (DMSO), acetone and ethanol,[1] but are poorly soluble in lipids. It is possible to increase curcuminoid solubility in aqueous phase with surfactants or co-surfactants.[2] Most common derivatives have different substituents on the phenyl groups.[1] There is an increasing demand for demethoxycurcumin, bisdemethoxycurcumin, and other curcuminoids because of their biological activity.[2]

  1. ^ a b Tiyaboonchai W, Tungpradit W, Plianbangchang P (June 2007). "Formulation and characterization of curcuminoids loaded solid lipid nanoparticles". Int J Pharm. 337 (1–2): 299–306. doi:10.1016/j.ijpharm.2006.12.043. PMID 17287099.
  2. ^ a b Jayaprakasha GK, Rao LJ, Sakariah KK (2006). "Antioxidant activities of curcumin, demethoxycurcumin and bisdemethoxycurcumin". Food Chemistry. 98 (4): 720–4. doi:10.1016/j.foodchem.2005.06.037.