| Cushing's syndrome disease | |
|---|---|
| Other names | hyperadrenocorticism, spontaneous hypercortisolism |
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| Dachshund with Cushing's syndrome. | |
| Specialty | Endocrinology |
| Symptoms | Enlarged stomach, lethargy, diabetes mellitus (cats) |
| Types | Pituitary dependent, adrenal dependent, iatrogenic |
| Risk factors | Certain breeds, bitches |
| Medication | Lysodren, trilostane, L-Deprenyl |
| Frequency | 0.2% to 0.28% of dogs. |
| Named after | Harvey Cushing |
Cushing's syndrome disease, also known as hyperadrenocorticism and spontaneous hypercortisolism, is a condition resulting from an endocrine disorder where too much adrenocorticotropic and cortisol hormones are produced, causing toxicity. It may arise in animals as well as in humans.[1] Cushing's is an umbrella term for conditions caused by elevated cortisol and adrenocorticotropic hormone levels.
Cushing's disease most commonly refers to pituitary-dependent hyperadrenocorticism, the most common condition of Cushing's syndrome, but 'Cushing's' is used to refer to all hyperadrenocorticism conditions.[2]
Cats are less likely to be diagnosed than dogs.[2] Cushing's occurs infrequently in hamsters. It may be more common but due to hamsters not being routinely treated it may go undiagnosed.[3]
- ^ Carotenuto, Gaia; Malerba, Eleonora; Dolfini, Costanza; Brugnoli, Francesca; Giannuzzi, Pasquale; Semprini, Giovanni; Tosolini, Paolo; Fracassi, Federico (2019-02-19). "Cushing's syndrome—an epidemiological study based on a canine population of 21,281 dogs". Open Veterinary Journal. 9 (1): 27–32. doi:10.4314/ovj.v9i1.5. ISSN 2218-6050. PMC 6500859. PMID 31086762.
- ^ a b Ward, Charlotte (March 2024). "Cushing's Syndrome". The New Zealand Veterinary Nurse. 30 (109): 21–25.
- ^ Rhodes, Karen Helton; Werner, Alexander H. (2011-01-25). Blackwell's Five-Minute Veterinary Consult Clinical Companion. Ames, Iowa: Wiley-Blackwell. p. 551-552. ISBN 978-0-8138-1596-1.