Cutaneous small-vessel vasculitis

Cutaneous small-vessel vasculitis
Other namesHypersensitivity vasculitis, allergic vasculitis
Example of hypersensitivity vasculitis
SpecialtyRheumatology, Immunology

Cutaneous small-vessel vasculitis (CSVV) is inflammation of small blood vessels, usually accompanied by small lumps beneath the skin.[1]: 831 [2] The condition is also known as hypersensitivity vasculitis, cutaneous leukocytoclastic vasculitis, hypersensitivity angiitis, cutaneous leukocytoclastic angiitis, cutaneous necrotizing vasculitis and cutaneous necrotizing venulitis,[3]

It is the most common form of vasculitis seen in clinical practice, usually caused by inflammation of post-capillary venules in the dermis).

"Leukocytoclastic" (literally meaning 'leukocyte-destroying') refers to the damage caused by nuclear debris from infiltrating neutrophils in and around the vessels.[4]

  1. ^ James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN 978-0-7216-2921-6.
  2. ^ Lotti T, Ghersetich I, Comacchi C, Jorizzo JL (November 1998). "Cutaneous small-vessel vasculitis". J. Am. Acad. Dermatol. 39 (5 Pt 1): 667–87, quiz 688–90. doi:10.1016/S0190-9622(98)70039-8. PMID 9810883. S2CID 26565263.
  3. ^ Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 978-1-4160-2999-1.
  4. ^ Harrison's Principles of Internal Medicine. 18th edition. Page 2798.