Cyanopeptolin

Cyanopeptolins (CPs) are a class of oligopeptides produced by Microcystis and Planktothrix algae strains, and can be neurotoxic.[1][2][3] The production of cyanopeptolins occurs through nonribosomal peptides synthases (NRPS).[4]

  1. ^ Susanne Faltermann; Sara Zucchi; Esther Kohler; Judith F. Blom; Jakob Pernthaler; Karl Fent (April 2014). "Molecular effects of the cyanobacterial toxin cyanopeptolin (CP1020) occurring in algal blooms: Global transcriptome analysis in zebrafish embryos" (PDF). Aquatic Toxicology. 149: 33–39. doi:10.1016/j.aquatox.2014.01.018. PMID 24561424.
  2. ^ Karl Gademann; Cyril Portmann; Judith F. Blom; Michael Zeder; Friedrich Jüttner (2010). "Multiple Toxin Production in the Cyanobacterium Microcystis: Isolation of the Toxic Protease Inhibitor Cyanopeptolin 1020" (PDF). J. Nat. Prod. 73 (5): 980–984. doi:10.1021/np900818c. PMID 20405925. Archived from the original (PDF) on 2022-02-02. Retrieved 2019-07-14.
  3. ^ Martin Welker; Hans Von Döhren (2006). "Cyanobacterial peptides – Nature's own combinatorial biosynthesis". FEMS Microbiology Reviews. 30 (4): 530–563. doi:10.1111/j.1574-6976.2006.00022.x. PMID 16774586.
  4. ^ Ramsy Agha; Samuel Cirés; Lars Wörmer; Antonio Quesada (2013). "Limited Stability of Microcystins in Oligopeptide Compositions of Microcystis aeruginosa (Cyanobacteria): Implications in the Definition of Chemotypes". Toxins. 5 (6): 1089–1104. doi:10.3390/toxins5061089. PMC 3717771. PMID 23744054.