Cyclin D3

CCND3
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3G33
Identifiers
Aliases	CCND3, cyclin D3
External IDs	OMIM: 123834; MGI: 88315; HomoloGene: 20419; GeneCards: CCND3; OMA:CCND3 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	42,050,357 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	47,910,616 bp
RNA expression pattern
	Top expressed in
	granulocyte; ; thymus; ; blood; ; spleen; ; lymph node; ; mononuclear cell; ; monocyte; ; right adrenal cortex; ; right lung; ; bone marrow;
	Top expressed in
	granulocyte; ; thymus; ; fetal liver hematopoietic progenitor cell; ; tibiofemoral joint; ; yolk sac; ; efferent ductule; ; human fetus; ; dermis; ; adrenal gland; ; atrium;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	cyclin-dependent protein serine/threonine kinase activity; protein binding; protein kinase binding; protein kinase activity; cyclin-dependent protein serine/threonine kinase regulator activity;
Cellular component	nucleoplasm; cyclin-dependent protein kinase holoenzyme complex; membrane; nucleus; cytoplasm;
Biological process	T cell proliferation; cell cycle; positive regulation of protein phosphorylation; signal transduction; positive regulation of cyclin-dependent protein serine/threonine kinase activity; regulation of cell cycle; cell division; negative regulation of transcription by RNA polymerase II; regulation of cell population proliferation; regulation of insulin receptor signaling pathway; regulation of cyclin-dependent protein serine/threonine kinase activity; mitotic cell cycle; protein phosphorylation; regulation of mitotic nuclear division; positive regulation of cell population proliferation; positive regulation of cell cycle; positive regulation of G1/S transition of mitotic cell cycle;
	Sources:Amigo / QuickGO
Orthologs
	896
	12445
	ENSG00000112576
	ENSMUSG00000034165
	P30281
	P30282
NM_001136017; NM_001136125; NM_001136126; NM_001287427; NM_001287434;
	NM_001760
	NM_001081635; NM_001081636; NM_007632
NP_001129489; NP_001129597; NP_001129598; NP_001274356; NP_001274363;
	NP_001751
	NP_001075104; NP_001075105; NP_031658
	Wikidata
View/Edit Human	View/Edit Mouse

G1/S-specific cyclin-D3 is a protein that in humans is encoded by the CCND3 gene.^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000112576 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000034165 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Inaba T, Matsushime H, Valentine M, Roussel MF, Sherr CJ, Look AT (July 1992). "Genomic organization, chromosomal localization, and independent expression of human cyclin D genes". Genomics. 13 (3): 565–574. doi:10.1016/0888-7543(92)90126-D. PMID 1386335.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000112576 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000034165 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid1386335-5] Inaba T, Matsushime H, Valentine M, Roussel MF, Sherr CJ, Look AT (July 1992). "Genomic organization, chromosomal localization, and independent expression of human cyclin D genes". Genomics. 13 (3): 565–574. doi:10.1016/0888-7543(92)90126-D. PMID 1386335.

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