D-class destroyer may refer to:
- D-class destroyer (1913), a class of Royal Navy torpedo boat destroyers
- C and D-class destroyer, a class of Royal Navy destroyers, built in 1930 and 1931
- Type 45 destroyer, a class of Royal Navy air defence destroyers, launched from 2006 to 2010
This disambiguation page lists articles associated with the title D-class destroyer.
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