DOK3

DOK3
Identifiers
Aliases	DOK3, DOKL, docking protein 3
External IDs	OMIM: 611435; MGI: 1351490; HomoloGene: 8448; GeneCards: DOK3; OMA:DOK3 - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	177,511,274 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	55,677,109 bp
RNA expression pattern
	Top expressed in
	monocyte; ; blood; ; granulocyte; ; spleen; ; right lung; ; lymph node; ; bone marrow; ; upper lobe of left lung; ; trabecular bone; ; appendix;
	Top expressed in
	granulocyte; ; blood; ; spleen; ; tibiofemoral joint; ; bone marrow; ; lymph node; ; mesenteric lymph nodes; ; fetal liver hematopoietic progenitor cell; ; stroma of bone marrow; ; subcutaneous adipose tissue;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding;
Cellular component	membrane; cytoplasm; plasma membrane; secretory granule membrane; ficolin-1-rich granule membrane;
Biological process	neutrophil degranulation; Ras protein signal transduction;
	Sources:Amigo / QuickGO
Orthologs
	79930
	27261
	ENSG00000146094
	ENSMUSG00000035711
	Q7L591
	Q9QZK7
NM_001144875; NM_001144876; NM_001308235; NM_001308236; NM_024872;
	NM_001375794; NM_001375795; NM_001375796; NM_001375797; NM_001375798; NM_001375799; NM_001384137; NM_001384138; NM_001384139
	NM_013739
NP_001138347; NP_001138348; NP_001295164; NP_001295165; NP_079148;
	NP_001362723; NP_001362724; NP_001362725; NP_001362726; NP_001362727; NP_001362728; NP_001371066; NP_001371067; NP_001371068
	NP_038767
	Wikidata
View/Edit Human	View/Edit Mouse

Docking protein 3 is a protein that in humans is encoded by the DOK3 gene.^[5]^[6]^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000146094 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000035711 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Lemay S, Davidson D, Latour S, Veillette A (Apr 2000). "Dok-3, a Novel Adapter Molecule Involved in the Negative Regulation of Immunoreceptor Signaling". Mol Cell Biol. 20 (8): 2743–54. doi:10.1128/MCB.20.8.2743-2754.2000. PMC 85490. PMID 10733577.
^ Favre C, Gerard A, Clauzier E, Pontarotti P, Olive D, Nunes JA (Feb 2003). "DOK4 and DOK5: new Dok-related genes expressed in human T cells". Genes Immun. 4 (1): 40–5. doi:10.1038/sj.gene.6363891. PMID 12595900. S2CID 24417010.
^ "Entrez Gene: DOK3 docking protein 3".